Pan Ying-Xiao, Guo Da-Wei, Li Xin, Liu Heng-Yi, Lu Shu-Lai
Dept. of Stomatology, Qingdao University & Dept. of Stomatology, Affiliated Qingdao Municipal Hospital, Qingdao University, Qigndao 266000, China.
Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Dec 1;38(6):681-686. doi: 10.7518/hxkq.2020.06.013.
Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa. The prevalence rate of OLP in adults is 0.5%-2%. The etiology and pathogenesis of OLP are still unclear. The pathogenesis of OLP may be related to the genetic polymorphism of some genes. Currently, the gene families, including tumor necrosis factor, interferon, interleukin, enzyme, and receptor, have been extensively studied. This work reviews related studies on gene polymorphism of OLP.
口腔扁平苔藓(OLP)是一种常见的口腔黏膜慢性炎症性疾病。成人OLP的患病率为0.5%-2%。OLP的病因和发病机制仍不清楚。OLP的发病机制可能与某些基因的遗传多态性有关。目前,包括肿瘤坏死因子、干扰素、白细胞介素、酶和受体等在内的基因家族已得到广泛研究。本文综述了OLP基因多态性的相关研究。