[锶的成骨机制研究进展]
[Research progress in the osteogenetic mechanism of strontium].
作者信息
Zhong Ning-Ying, Wang Li-Ping
机构信息
Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatological Hospital of Guangzhou Medical University, Guangzhou 510140, China;Stomatology Center, Shunde Hospital, Southern Medical University The First People's Hospital of Shunde, Foshan 528308, China.
Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatological Hospital of Guangzhou Medical University, Guangzhou 510140, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2020 Dec 1;38(6):697-703. doi: 10.7518/hxkq.2020.06.016.
Strontium (Sr) is an essential trace element and widely exists in nature. It plays an important role in the in vivo regulation of bone metabolism. Sr locates below Fe in the periodic table, and its chemical structure and polarity are similar to those of Ca. It can induce bone mesenchymal stem cells to differentiate into osteoblasts by inhibiting the activity of osteoclasts and reducing bone resorption. It promotes bone formation through a series of related pathways. The mechanism of Sr regulation of bone metabolism has been extensively researched in recent years. The current study aims to investigate the mechanism of Sr and provide a theoretical basis for its clinical application.
锶（Sr）是一种必需的微量元素，广泛存在于自然界中。它在体内骨代谢调节中起重要作用。锶在元素周期表中位于铁之下，其化学结构和极性与钙相似。它可以通过抑制破骨细胞的活性和减少骨吸收来诱导骨间充质干细胞分化为成骨细胞。它通过一系列相关途径促进骨形成。近年来，锶调节骨代谢的机制已得到广泛研究。当前的研究旨在探究锶的作用机制，并为其临床应用提供理论依据。
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