Kuzmenko A V, Kuzmenko V V, Gyaurgiev T A
Voronezh State Medical University n.a. N.N. Burdenko, Voronezh, Russia.
Urologiia. 2020 Dec(6):52-57.
Every year, more than 7 million women go to the doctor for chronic cystitis. An important factor is the psychoemotional component of this disease.
comparative analysis of various options for complex treatment of women with chronic recurrent bacterial cystitis using phototherapy, chronotherapy and correction of psychoemotional disorders with the anxiolytic drug Adaptol.
90 women with chronic recurrent bacterial cystitis in the acute stage were examined and divided into 3 groups of 30 people. In group 1, patients received basic therapy with Furamag (furazidin kalium). In group 2, patients received standard therapy in combination with phototherapy in the acrophase of the chronorhythm. In group 3, basic therapy was performed in combination with phototherapy in the acrophase of the chronorhythm and Adaptol. The severity of dysuria and pain, leukocyturia, bacteriuria, chronobiological and psychoemotional status were evaluated.
Initially, all patients showed signs of desynchronosis and psychoemotional disorders. All groups showed signs of exacerbation of chronic cystitis. The results obtained on the 5th day of therapy in groups 2 and 3 were statistically significantly different (p<0.05) from those in group 1. In group 3, the number of nocturnal urination (0.9+/-0.7), the number of imperative urges per day (0.7+/-0.5), and the intensity of pain (0.7+/-0.6) were the closest to normal. By day 10, clinical and laboratory parameters in all three groups reached normal values, which indicates the effectiveness of the therapy in each of the groups.
Thus, the use of Furamag and Adaptol in combination with phototherapy at the maximum peaks of psychoemotional and physiological activity of the body effectively stops the clinical and laboratory manifestations of the disease, corrects the mental status and improves the quality of life of women in a shorter period of treatment.
每年有超过700万女性因慢性膀胱炎就医。该疾病的一个重要因素是其心理情绪成分。
比较采用光疗、时间疗法以及使用抗焦虑药物阿普唑仑纠正心理情绪障碍等多种方案对慢性复发性细菌性膀胱炎女性患者进行综合治疗的效果。
对90例处于急性期的慢性复发性细菌性膀胱炎女性患者进行检查，并将其分为3组，每组30人。第1组患者接受用呋喃马唑（呋喃唑酮钾）进行的基础治疗。第2组患者在生理节律的高峰期接受标准治疗并联合光疗。第3组患者在生理节律的高峰期接受基础治疗并联合光疗及阿普唑仑。评估排尿困难和疼痛的严重程度、白细胞尿、菌尿、时间生物学和心理情绪状态。
最初，所有患者均表现出不同步和心理情绪障碍的迹象。所有组均出现慢性膀胱炎加重的迹象。第2组和第3组在治疗第5天获得的结果与第1组相比有统计学显著差异（p<0.05）。在第3组中，夜间排尿次数（0.9±0.7）、每日急迫性尿意次数（0.7±0.5）以及疼痛强度（0.7±0.6）最接近正常。到第10天时，所有三组的临床和实验室参数均达到正常值，这表明每组治疗均有效。
因此，在机体心理情绪和生理活动的最大峰值时，联合使用呋喃马唑和阿普唑仑并结合光疗可有效阻止疾病的临床和实验室表现，纠正精神状态，并在较短治疗期内改善女性的生活质量。
