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恶性叶状肿瘤伴脂肪肉瘤分化:细胞学诊断。

Malignant phyllodes tumor with liposarcomatous differentiation: Diagnosed on cytology.

机构信息

Department of Pathology and Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

出版信息

Diagn Cytopathol. 2021 Jun;49(6):E226-E230. doi: 10.1002/dc.24681. Epub 2020 Dec 30.

Abstract

Phyllodes tumor (PT) accounts for less than 1% of all primary tumors of the breast and 2% to 3% of all fibroepithelial lesions. We report a case of heterologous liposarcomatous elements in a malignant PT of the breast on Fine needle aspiration cytology (FNAC) and later confirmed by histopathological examination. A 58-years-old woman presented with a huge breast mass for which FNAC was done. Cytology showed features of malignant PT with a good representation of heterologous liposarcomatous areas. The cytological findings were in concordance with the histologic features. Malignant PT and its various heterologous elements of stroma can be diagnosed on FNA cytology when performed optimally. They can be vital for the preoperative assessment of patients suspected with malignancy to formulate the surgical plan accordingly.

摘要

叶状肿瘤(PT)占所有乳腺原发性肿瘤的不到 1%,占所有纤维上皮病变的 2%至 3%。我们报告了一例在乳腺恶性 PT 中的异源性脂肪肉瘤成分,该病例通过细针抽吸细胞学检查(FNAC)发现,随后通过组织病理学检查得到证实。一名 58 岁女性因巨大乳腺肿块就诊,接受了 FNAC 检查。细胞学检查显示恶性 PT 的特征,并有很好的异源性脂肪肉瘤区域表现。细胞学发现与组织学特征一致。当进行最佳操作时,FNAC 细胞学可以诊断恶性 PT 及其各种异源性基质成分。对于疑似恶性肿瘤的患者,术前评估至关重要,有助于制定相应的手术计划。

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