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韩国青年人群自杀死亡率相关的社会人口因素、健康行为和生物学指标:一项涉及 1500 万男女的全国队列研究。

Sociodemographic Factors, Health Behaviors, and Biological Indicators Associated With Suicide Mortality Among Young Adults in South Korea: A Nationwide Cohort Study Among 15 Million Men and Women.

机构信息

Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.

出版信息

J Clin Psychiatry. 2020 Dec 29;82(1):19m13037. doi: 10.4088/JCP.19m13037.

Abstract

OBJECTIVE

The role of sociodemographic factors, health behaviors, and biological indicators as potential risk factors for suicide is relatively understudied among young adults. The aim of this study is to explore the association of these variables with the risk of death by suicide among young adults.

METHODS

The study population consisted of 15,534,438 individuals aged 20-39 years from the Korean National Health Insurance Service. Sociodemographic factors associated with death by suicide during 2006-2015 were evaluated. 3,396,353 individuals who underwent health examinations between 2002 and 2005 were separately assessed for health behaviors and biological indicators associated with death by suicide. Cox proportional hazards regression analysis was used to determine the hazard ratios (HRs) and 95% confidence intervals (CIs) for suicide mortality according to sociodemographic factors (age, household income, job status, residence, and Charlson comorbidity index score), health behaviors (physical activity, smoking, and alcohol consumption), and biological indicators (blood pressure, total cholesterol level, body mass index, and fasting serum glucose level).

RESULTS

Low household income, self- and non-employment, increased comorbidity, smoking, and normal weight elevated the risk of death by suicide among young adults. While older age was associated with elevated risk for death by suicide among men (adjusted HR [aHR] = 2.11; 95% CI, 2.02-2.20 for men aged 35-39 years), older age reduced the risk for death by suicide among women (aHR = 0.72; 95% CI, 0.69-0.75 for women aged 35-39 years). Elevated blood pressure and fasting serum glucose level were associated with increased risk for death by suicide among men (aHR = 1.16; 95% CI, 1.05-1.28 and aHR = 1.48; 95% CI, 1.26-1.75, respectively). Finally, high total cholesterol levels were associated with increased risk for death by suicide among women (aHR = 1.59; 95% CI, 1.19-2.13).

CONCLUSIONS

Sociodemographic factors, health behaviors, and biological indicators were associated with suicide mortality among young adults.

摘要

目的

社会人口因素、健康行为和生物指标作为自杀的潜在危险因素,在年轻成年人中研究相对较少。本研究旨在探讨这些变量与年轻成年人自杀死亡风险的关系。

方法

研究人群为来自韩国国家健康保险服务的 15534438 名 20-39 岁个体。评估了 2006-2015 年期间与自杀死亡相关的社会人口因素。另外,对 2002 年至 2005 年期间接受健康检查的 3396353 名个体,评估了与自杀死亡相关的健康行为和生物指标。采用 Cox 比例风险回归分析,根据社会人口因素(年龄、家庭收入、工作状态、居住和 Charlson 合并症指数评分)、健康行为(体力活动、吸烟和饮酒)和生物指标(血压、总胆固醇水平、体重指数和空腹血清葡萄糖水平),确定自杀死亡率的危险比(HRs)和 95%置信区间(CIs)。

结果

低家庭收入、自雇和非自雇、合并症增加、吸烟和正常体重均增加了年轻成年人自杀死亡的风险。而年龄较大与男性自杀死亡风险增加相关(调整后的 HR[aHR] = 2.11;95%CI,2.02-2.20,年龄 35-39 岁的男性),而年龄较大降低了女性自杀死亡的风险(aHR = 0.72;95%CI,0.69-0.75,年龄 35-39 岁的女性)。较高的血压和空腹血清葡萄糖水平与男性自杀死亡风险增加相关(aHR = 1.16;95%CI,1.05-1.28 和 aHR = 1.48;95%CI,1.26-1.75)。最后,高总胆固醇水平与女性自杀死亡风险增加相关(aHR = 1.59;95%CI,1.19-2.13)。

结论

社会人口因素、健康行为和生物指标与年轻成年人的自杀死亡率相关。

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