Department of Medicine and Therapeutics University of Ghana Medical School, College of Health Sciences, University of Ghana, Accra, Ghana.
Departments of Biostatistics, School of Public Health, College of Health Sciences, University of Ghana, Accra, Ghana.
PLoS One. 2020 Dec 30;15(12):e0244437. doi: 10.1371/journal.pone.0244437. eCollection 2020.
Kidney transplantation is the preferred treatment for patients with end stage renal disease. However, it is largely unavailable in many sub-Sahara African countries including Ghana. In Ghana, treatment for end stage renal disease including transplantation, is usually financed out-of-pocket. As efforts continue to be made to expand the kidney transplantation programme in Ghana, it remains unclear whether patients with Chronic Kidney Disease (CKD) would be willing to pay for a kidney transplant.
The aim of the study was to assess CKD patients' willingness to pay for kidney transplantation as a treatment option for end stage renal disease in Ghana.
A facility based cross-sectional study conducted at the Renal Outpatient clinic and Dialysis Unit of Korle-Bu Teaching Hospital among 342 CKD patients 18 years and above including those receiving haemodialysis. A consecutive sampling approach was used to recruit patients. Structured questionnaires were administered to obtain information on demographic, socio-economic, knowledge about transplant, perception of transplantation and willingness to pay for transplant. In addition, the INSPIRIT questionnaire was used to assess patients' level of religiosity and spirituality. Contingent valuation method (CVM) method was used to assess willingness to pay (WTP) for kidney transplantation. Logistic regression model was used to determine the significant predictors of WTP.
The average age of respondents was 50.2 ± 17.1 years with most (56.7% (194/342) being male. Overall, 90 out of the 342 study participants (26.3%, 95%CI: 21.7-31.3%) were willing to pay for a kidney transplant at the current going price (≥ $ 17,550) or more. The median amount participants were willing to pay below the current price was $986 (IQR: $197 -$1972). Among those willing to accept (67.3%, 230/342), 29.1% (67/230) were willing to pay for kidney transplant at the prevailing price. Wealth quintile, social support in terms of number of family friends one could talk to about personal issues and number of family members one can call on for help were the only factors identified to be significantly predictive of willingness to pay (p-value < 0.05).
The overall willingness to pay for kidney transplant is low among chronic kidney disease patients attending Korle-Bu Teaching Hospital. Patients with higher socio-economic status and those with more family members one can call on for help were more likely to pay for kidney transplantation. The study's findings give policy makers an understanding of CKD patients circumstances regarding affordability of the medical management of CKD including kidney transplantation. This can help develop pricing models to attain an ideal poise between a cost effective but sustainable kidney transplant programme and improve patient access to this ultimate treatment option.
肾移植是终末期肾病患者的首选治疗方法。然而,在包括加纳在内的许多撒哈拉以南非洲国家,肾移植服务仍难以普及。在加纳,包括移植在内的终末期肾病治疗通常需要自费。随着扩大肾移植项目的努力不断推进,目前尚不清楚慢性肾脏病(CKD)患者是否愿意为肾移植付费。
本研究旨在评估加纳 CKD 患者对支付肾移植费用作为终末期肾病治疗选择的意愿。
这是一项在科勒布教学医院肾脏门诊和透析室进行的基于机构的横断面研究,纳入了 342 名年龄在 18 岁及以上的 CKD 患者,包括正在接受血液透析的患者。采用连续抽样方法招募患者。使用结构化问卷获取人口统计学、社会经济、移植知识、对移植的看法以及支付移植费用的意愿等信息。此外,还使用 INSPIRIT 问卷评估患者的宗教信仰和精神信仰水平。使用条件价值评估法(CVM)评估对肾移植的支付意愿(WTP)。使用逻辑回归模型确定支付意愿的显著预测因素。
受访者的平均年龄为 50.2 ± 17.1 岁,其中 56.7%(194/342)为男性。总体而言,342 名研究参与者中有 90 名(26.3%,95%CI:21.7-31.3%)愿意以当前的现行价格(≥$17550)或更高价格支付肾移植费用。参与者愿意支付的中位数金额低于现行价格为$986(IQR:$197 -$1972)。在愿意接受的患者中(67.3%,230/342),29.1%(67/230)愿意支付当前价格的肾移植费用。财富五分位数、可以谈论个人问题的家庭朋友数量以及可以求助的家庭成员数量是唯一被确定为支付意愿的显著预测因素(p 值<0.05)。
在科勒布教学医院就诊的慢性肾脏病患者中,整体支付肾移植费用的意愿较低。社会经济地位较高和可以求助的家庭成员较多的患者更有可能支付肾移植费用。该研究结果使决策者了解慢性肾脏病患者在支付慢性肾脏病的医疗管理费用(包括肾移植)方面的情况。这有助于制定定价模型,在具有成本效益但可持续的肾移植项目和改善患者获得这种最终治疗选择之间取得理想的平衡。