实验性诱导大鼠髁突吸收中颞下颌关节机械感受器的功能变化。
Functional changes in the temporomandibular joint mechanoreceptors associated with experimentally induced condylar resorption in rats.
出版信息
Angle Orthod. 2020 Nov 1;90(6):831-836. doi: 10.2319/020420-80.1.
OBJECTIVES
To evaluate the influence of experimentally induced progressive condylar resorption (PCR) on temporomandibular joint (TMJ) mechanoreception.
MATERIALS AND METHODS
Twenty 13-week-old male albino Wistar rats were divided equally into control and PCR groups. A compressive force was loaded on the left TMJ of PCR group rats to induce condylar resorption. Single-unit activities of TMJ mechanoreceptors were also induced through passive jaw movement. Recording was performed for the left Gasserian ganglion at 3 days and 1 week after the establishment of PCR group. The effects of PCR on TMJ units were assessed by measuring the firing threshold, maximum instantaneous firing frequency, and average firing frequency.
RESULTS
Compared with the control group, there were no significant differences in the firing threshold of the PCR group after 3 days. The thresholds were significantly higher 1 week after compressive force loading on the condyle. The maximum instantaneous firing frequencies and the average firing frequencies showed no significant differences after 3 days. However, these were significantly lower 1 week after compressive force loading.
CONCLUSIONS
The findings suggest that compressive force loading on the condyle may influence the function of TMJ mechanoreceptors.
目的
评估实验性进行性髁突吸收（PCR）对颞下颌关节（TMJ）机械感受器的影响。
材料和方法
将 20 只 13 周龄雄性白化 Wistar 大鼠平均分为对照组和 PCR 组。PCR 组大鼠左侧 TMJ 施加压缩力以诱导髁突吸收。通过被动下颌运动也诱导 TMJ 机械感受器的单个单位活动。在建立 PCR 组后 3 天和 1 周，记录左侧三叉神经节的记录。通过测量放电阈值、最大瞬时放电频率和平均放电频率来评估 PCR 对 TMJ 单位的影响。
结果
与对照组相比，PCR 组在 3 天后的放电阈值没有显著差异。在施加于髁突的压缩力后 1 周，阈值明显升高。3 天后最大瞬时放电频率和平均放电频率没有显著差异。然而，在施加于髁突的压缩力后 1 周，这些频率明显降低。
结论
这些发现表明，施加于髁突的压缩力可能会影响 TMJ 机械感受器的功能。
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