Chirurgia (Bucur). 2020 Nov-Dec;115(6):767-774. doi: 10.21614/chirurgia.115.6.767.
Development of seroma after incisional hernia repair is a common complication. Our study aims to compare the outcomes of sublay incisional hernia repairs with or without spray instillation of fibrin glue. We enrolled fifty patients undergoing incisional hernia repair. In all patients a suction drain was placed in the subcutaneous space. In one group (FG) 4 ml fibrin glue was instilled in the subcutaneous space. In the control group (C) patients did not receive any prevention measure. Wounds fluids were collected on post-operative day 1 (POD) and once daily until drain removal. All patients were followed up by ultrasound on POD 15, 20, 40, 60. Drain fluid production, even if in significantly greater amount in the C group (p 0.01) as compared with the FG group, decreased after POD 1 in both groups. Drain was removed on POD-5 in 80% of FG patients and in 36% of C patients (p 0.01). No infective or bleeding complications were detected. In group FG average hospital stay was of 5.5 ÃÂ+- 2 days versus 7.1 +- 1.5 days in group C (p 0.01). At ultrasounds examination, seroma development was similar among two groups. Spray instillation of fibrin glue during the surgical repair reduces amount of drained fluid and hospital stay without increasing surgical complications. However, seroma occurrence was not significantly reduced.
切口疝修补术后发生血清肿是一种常见的并发症。我们的研究旨在比较使用或不使用纤维蛋白胶喷涂的皮下修补术治疗切口疝的效果。我们纳入了 50 名接受切口疝修补术的患者。所有患者均在皮下放置了引流管。在一组（FG 组）中，在皮下空间中注入了 4 毫升纤维蛋白胶。在对照组（C 组）中，患者未接受任何预防措施。在术后第 1 天（POD）和每天一次，直到引流管移除时收集伤口液。所有患者均在 POD 15、20、40、60 进行超声随访。引流液的产生，即使在 C 组中明显多于 FG 组（p 0.01），但在两组中均在 POD 1 后减少。FG 组 80%的患者在 POD-5 时拔除引流管，而 C 组中 36%的患者（p 0.01）。未发现感染或出血并发症。FG 组的平均住院时间为 5.5 ± 2 天，而 C 组为 7.1 ± 1.5 天（p 0.01）。在超声检查中，两组的血清肿发展情况相似。在手术修复过程中喷洒纤维蛋白胶可减少引流液量和住院时间，而不会增加手术并发症。然而，血清肿的发生并没有明显减少。
