Chirurgia (Bucur). 2020 Nov-Dec;115(6):775-782. doi: 10.21614/chirurgia.115.6.775.
To investigate the cure rate and adverse effects of silver nitrate application for treatment of pilonidal sinus disease (PSD). Number of sinus pit orifices, and complications with silver nitrate application and debridement for sacrococcygeal PSD between January 2015 and July 2018 were analyzed in this retrospective study. Data were obtained from surgical, discharge, and outpatient follow-up records. Among 56 patients who were treated with silver nitrate stick, 11 patients with incomplete hospital records were excluded from the study. Demographic data including age, gender, length of follow-up, number of silver nitrate applications, number of involved sinuses and recurrence and complication rates were recorded. Results were expressed as frequencies, means, and range of values. The Mann Whitney U and chi square tests were used to evaluate significance. Mean age was 24.3 +- 5.18 (range, 14 - 36) years, and recurrence occurred in 4 (8.9%) patients. Complications developed in 10 (22.2%) patients and included abscess, erythema, and necrosis in 5 (11.1%), 2 (4.4%), and 3 (6.6%) patients, respectively. The recurrence rate was significantly higher in patients who developed abscesses during the follow-up period (p = 0.001) than those who did not. There was no statistically significant correlation between the recurrence rate and number of sinuses or the number of silver nitrate applications.
Low morbidity and high healing rates achieved with silver nitrate provide support for this application as a feasible and effective conservative outpatient treatment for PSD in certain patients.
探讨硝酸银治疗藏毛窦疾病(PSD)的治愈率和不良反应。本回顾性研究分析了 2015 年 1 月至 2018 年 7 月期间采用硝酸银应用和清创术治疗骶尾部 PSD 的窦道数量和并发症。数据来自手术、出院和门诊随访记录。在 56 例接受硝酸银棒治疗的患者中,有 11 例因住院记录不完整而被排除在研究之外。记录了包括年龄、性别、随访时间、硝酸银应用次数、受累窦道数量以及复发和并发症发生率等人口统计学数据。结果以频率、平均值和值范围表示。采用 Mann-Whitney U 检验和卡方检验评估显著性。平均年龄为 24.3 +- 5.18(范围 14-36)岁,有 4 例(8.9%)患者复发。10 例(22.2%)患者出现并发症,包括脓肿、红斑和坏死,分别为 5 例(11.1%)、2 例(4.4%)和 3 例(6.6%)。在随访期间发生脓肿的患者复发率明显更高(p=0.001)。复发率与窦道数量或硝酸银应用次数之间无统计学显著相关性。
硝酸银具有较低的发病率和较高的愈合率,为该应用提供了支持,表明其在某些患者中是一种可行且有效的保守门诊治疗 PSD 的方法。