Department of Surgery, Stanford University School of Medicine, 453 Quarry Road, Stanford, CA, 94305, USA.
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Pediatr Surg Int. 2024 Aug 15;40(1):227. doi: 10.1007/s00383-024-05821-x.
Patients with pilonidal disease (PD) can present with concurrent draining secondary sinus at the superior gluteal cleft. The natural disease course in the setting of this severe phenotype is poorly characterized. We present the largest cohort of patients with PD and concurrent secondary sinus.
Patients with PD and concurrent secondary sinus who underwent Gips procedure with secondary sinus excision from 2019 to 2023 were prospectively followed. Patient demographics, drainage recurrence, symptom resolution, treatment, and follow-up period were recorded. Recurrent drainage from previous secondary sinus site was defined as isolated painless serous drainage after the wound had closed for > 3 weeks; recurrent PD was characterized as recurrent pain and bloody drainage after excision.
One hundred and five patients (seventy-one males) with a median age of 17.2 years [interquartile range (IQR):15.4-19.0] underwent excision of their disease and were followed for a median of 367.0 days (IQR: 173.2-658.8). Without regular epilation, six patients (5.7%, five males, one female) had recurrent PD. With regular epilation, three patients (2.8%, three males) had recurrent PD. Eight patients (7.5%, six males, two females) had recurrent secondary sinus site drainage. Median time to recurrent drainage was 75.5 days (IQR: 65.2-216.2) after excision and for recurrent drainage to resolve was 72 days (IQR: 49-81). Recurrent secondary sinus site drainage was treated with antibiotics, silver nitrate, debridement, or no treatment.
Patients who present with PD in the setting of concurrent secondary sinus have a unique, more severe disease phenotype. Excision can be complicated by recurrent drainage from the secondary sinus site that can resolve without repeat surgical excision.
患有藏毛窦病(PD)的患者可能在臀上部裂隙存在并发的引流性二级窦道。在这种严重表型下,其自然疾病过程尚未得到充分描述。我们报告了最大的 PD 并发二级窦道患者队列。
前瞻性随访了 2019 年至 2023 年间接受 Gips 手术和二级窦道切除的 PD 并发二级窦道患者。记录患者的人口统计学特征、引流复发、症状缓解、治疗和随访时间。既往二级窦道部位的复发性引流定义为伤口愈合后超过 3 周出现无疼痛的浆液性引流;复发性 PD 的特征是切除后出现疼痛和血性引流。
105 例患者(71 例男性)的中位年龄为 17.2 岁(四分位距 [IQR]:15.4-19.0),接受了疾病切除并随访了中位时间为 367.0 天(IQR:173.2-658.8)。未定期除毛的 6 例患者(5.7%,5 例男性,1 例女性)出现复发性 PD。定期除毛的 3 例患者(2.8%,3 例男性)出现复发性 PD。8 例患者(7.5%,6 例男性,2 例女性)出现二级窦道部位引流复发。切除后复发引流的中位时间为 75.5 天(IQR:65.2-216.2),复发引流缓解的中位时间为 72 天(IQR:49-81)。二级窦道部位引流复发的治疗方法包括抗生素、硝酸银、清创术或不治疗。
在并发二级窦道的 PD 患者中,存在独特的、更严重的疾病表型。二级窦道切除后可能并发复发性引流,但无需再次手术切除即可缓解。