[胆道癌免疫治疗的进展]
[Advance in immunotherapy on biliary tract cancers].
作者信息
Liu L G, Zhang Y J, Wang X A, Liu Y B
机构信息
Department of Biliary-Pancreatic Surgery,Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine;Shanghai Key Laboratory of Biliary Tract Disease Research; Shanghai Research Center of Biliary Tract Disease; State Key Laboratory for Oncogenes and Related Genes,Shanghai 200127,China.
出版信息
Zhonghua Wai Ke Za Zhi. 2021 Feb 1;59(2):156-160. doi: 10.3760/cma.j.cn112139-20200515-00382.
Biliary tract cancers(BTC),including gallbladder cancer and cholangiocarcinoma,has the characteristics of low early diagnosis rate,complex anatomy,insensitivity to radiotherapy and chemotherapy, and poor prognosis.In recent years,immunotherapy as a new method,has made great progress in the treatment of advanced malignant tumors.Immunotherapy is gradually applied in the treatment of BTC,such as inhibitory agents targeting the immune checkpoint receptor pathway,adoptive immunotherapy and tumor vaccines.
胆道癌（BTC），包括胆囊癌和胆管癌，具有早期诊断率低、解剖结构复杂、对放疗和化疗不敏感以及预后差等特点。近年来，免疫疗法作为一种新方法，在晚期恶性肿瘤的治疗中取得了巨大进展。免疫疗法正逐渐应用于BTC的治疗，如针对免疫检查点受体途径的抑制剂、过继性免疫疗法和肿瘤疫苗。
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