Romanova L K, Mladkovskaia T B, Pokrovskaia M S, Ovcharenko S I, Filippov V V
Biull Eksp Biol Med. 1988 Jan;105(1):74-7.
Endopulmonary cytograms and mitotic activity of alveolar macrophages (AM) in the bronchoalveolar lavage (BAL) from 30 patients with diffuse lung pathology have been studied. AM mitosis was found in 24 cases. Mitotic index for all the patients was 0.65% and ranged from 0.25 to 2.75%. Electron microscopy revealed the capacity of differentiated forms of AM for mitotic division. Free AM may be regarded as slowly proliferating cell population, capable of self-reproduction in lung pathology.
对30例弥漫性肺部病变患者支气管肺泡灌洗(BAL)中的肺内细胞图谱及肺泡巨噬细胞(AM)的有丝分裂活性进行了研究。在24例中发现了AM有丝分裂。所有患者的有丝分裂指数为0.65%,范围在0.25%至2.75%之间。电子显微镜显示分化形式的AM具有有丝分裂能力。游离的AM可被视为缓慢增殖的细胞群体,在肺部病变时能够自我复制。