Opt Express. 2020 Nov 23;28(24):35427-35437. doi: 10.1364/OE.402467.
Optical interrogation of tissues is broadly considered in biomedical applications. Nevertheless, light scattering by tissue limits the resolution and accuracy achieved when investigating sub-surface tissue features. Light carrying optical angular momentum or complex polarization profiles, offers different propagation characteristics through scattering media compared to light with unstructured beam profiles. Here we discuss the behaviour of structured light scattered by tissue-mimicking phantoms. We study the spatial and the polarization profile of the scattered modes as a function of a range of optical parameters of the phantoms, with varying scattering and absorption coefficients and of different lengths. These results show the non-trivial trade-off between the advantages of structured light profiles and mode broadening, stimulating further investigations in this direction.
光学检测在生物医学领域得到了广泛的应用。然而，组织的光散射限制了在研究亚表面组织特征时所能达到的分辨率和准确性。与具有非结构化光束轮廓的光相比，携带光学角动量或复杂偏振分布的光在散射介质中的传播特性有所不同。在这里，我们讨论了模拟组织的光散射的结构光的行为。我们研究了散射模式的空间和偏振分布作为一系列光学参数的函数，包括不同的散射和吸收系数以及不同的长度。这些结果表明，在结构光轮廓和模式展宽的优势之间存在着复杂的权衡，这激发了在这一方向上的进一步研究。
