Löfgren M, Andersson I, Bondeson L, Lindholm K
Department of Diagnostic Radiology, Malmö General Hospital, Sweden.
Cancer. 1988 Mar 1;61(5):1032-7. doi: 10.1002/1097-0142(19880301)61:5<1032::aid-cncr2820610529>3.0.co;2-r.
X-ray guided localization of 215 nonpalpable, mammographically detected, breast lesions for fine-needle aspiration biopsy was performed using a two-dimensional coordinate grid. Representative material was obtained in 64% of the lesions. Very strict criteria of representativity were observed. The sensitivity of the cytologic procedure was 92%, the specificity 95%, the predictive value of positive cytologic diagnosis 88%, and the predictive value of a negative cytologic diagnosis 97%. Potential pitfalls in the localization and aspiration procedures are discussed. The results of cytologic examination should always be correlated with the mammographic findings, and further diagnostic and therapeutic decisions should be based on both modalities. In this setting, x-ray guided fine-needle aspiration cytologic study is a highly valuable diagnostic tool.
使用二维坐标网格对215个乳腺钼靶检查发现但触诊不到的乳腺病变进行X线引导下定位，以进行细针穿刺活检。64%的病变获取到了代表性样本。采用了非常严格的代表性标准。细胞学检查的敏感性为92%，特异性为95%，阳性细胞学诊断的预测值为88%，阴性细胞学诊断的预测值为97%。讨论了定位和穿刺过程中的潜在陷阱。细胞学检查结果应始终与乳腺钼靶检查结果相关联，进一步的诊断和治疗决策应基于这两种检查方式。在这种情况下，X线引导下细针穿刺细胞学研究是一种非常有价值的诊断工具。
