• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

心房颤动与卒中预防:最新进展——流行病学与病理生理学:新的危险因素、概念及争议

Atrial fibrillation and stroke prevention: state of the art-epidemiology and pathophysiology: new risk factors, concepts and controversies.

作者信息

Kodani Eitaro, Akao Masaharu

机构信息

Department of Cardiovascular Medicine, Nippon Medical School Tama-Nagayama Hospital, 1-7-1, Nagayama, Tama-shi, Tokyo 206-8512, Japan.

Department of Cardiology, National Hospital Organization Kyoto Medical Center, 1-1, Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto 612-8555, Japan.

出版信息

Eur Heart J Suppl. 2020 Dec 22;22(Suppl O):O1-O13. doi: 10.1093/eurheartj/suaa176. eCollection 2020 Dec.

DOI:10.1093/eurheartj/suaa176
PMID:33380940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7753870/
Abstract

Atrial fibrillation (AF) increases the risk of thromboembolism, and risk assessment for thromboembolism is necessary for the management of AF patients. CHADS2 and CHA2DS2-VASc scores have been adopted in international guidelines for AF management, but the significance of each risk factor included in these risk scores are sometimes controversial, and the performance of these scores is only modest. There are several other risk factors not included in the scores such as renal dysfunction, low body weight, type of AF (paroxysmal or non-paroxysmal) as well as echocardiographic parameters and blood biomarkers, and physicians should assess patients risk in an integrated manner.

摘要

心房颤动(AF)会增加血栓栓塞风险,对于房颤患者的管理而言,进行血栓栓塞风险评估很有必要。CHADS2和CHA2DS2-VASc评分已被纳入房颤管理的国际指南,但这些风险评分中所包含的各个风险因素的意义有时存在争议,且这些评分的表现也只是一般。还有一些风险因素未包含在这些评分中,如肾功能不全、低体重、房颤类型(阵发性或非阵发性)以及超声心动图参数和血液生物标志物,医生应综合评估患者的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/8cf6eb8004b5/suaa176f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/fca98978d25c/suaa176f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/504b9dad2ee1/suaa176f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/8cf6eb8004b5/suaa176f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/fca98978d25c/suaa176f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/504b9dad2ee1/suaa176f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f832/7753870/8cf6eb8004b5/suaa176f3.jpg

相似文献

1
Atrial fibrillation and stroke prevention: state of the art-epidemiology and pathophysiology: new risk factors, concepts and controversies.心房颤动与卒中预防:最新进展——流行病学与病理生理学:新的危险因素、概念及争议
Eur Heart J Suppl. 2020 Dec 22;22(Suppl O):O1-O13. doi: 10.1093/eurheartj/suaa176. eCollection 2020 Dec.
2
Renal dysfunction, stroke risk scores (CHADS2, CHA2DS2-VASc, and R2CHADS2), and the risk of thromboembolic events after catheter ablation of atrial fibrillation: the Leipzig Heart Center AF Ablation Registry.肾功能障碍、卒中风险评分(CHADS2、CHA2DS2-VASc 和 R2CHADS2)与心房颤动导管消融术后血栓栓塞事件风险:莱比锡心脏中心房颤消融登记研究。
Circ Arrhythm Electrophysiol. 2013 Oct;6(5):868-74. doi: 10.1161/CIRCEP.113.000869. Epub 2013 Sep 18.
3
Relation of red blood cell distribution width with CHADS and CHADS-VASc score in Chinese patients with non-valvular atrial fibrillation.中国非瓣膜性心房颤动患者红细胞分布宽度与CHADS及CHADS-VASc评分的关系
Int J Cardiol. 2017 Feb 1;228:861-864. doi: 10.1016/j.ijcard.2016.11.255. Epub 2016 Nov 14.
4
Refinement of CHADS2 and CHA2DS2-VASc scores predict left atrial thrombus or spontaneous echo contrast in nonvalvular atrial fibrillation patients.CHADS2 和 CHA2DS2-VASc 评分的细化可预测非瓣膜性心房颤动患者左心房血栓或自发性回声对比。
J Int Med Res. 2022 Jan;50(1):3000605221074520. doi: 10.1177/03000605221074520.
5
Association between big endothelin-1 and CHADS/CHADS-VASc scores in non-valvular atrial fibrillation.非瓣膜性心房颤动中大分子内皮素-1与CHADS/CHADS-VASc评分之间的关联
J Geriatr Cardiol. 2019 Nov;16(11):812-817. doi: 10.11909/j.issn.1671-5411.2019.11.003.
6
The value of the CHA2DS2-VASc score for refining stroke risk stratification in patients with atrial fibrillation with a CHADS2 score 0-1: a nationwide cohort study.CHA2DS2-VASc 评分在 CHADS2 评分为 0-1 的房颤患者中对卒中风险分层的价值:一项全国性队列研究。
Thromb Haemost. 2012 Jun;107(6):1172-9. doi: 10.1160/TH12-03-0175. Epub 2012 Apr 3.
7
Left atrial spontaneous echo contrast occurring in patients with low CHADS or CHADS-VASc scores.在 CHADS 或 CHADS-VASc 评分较低的患者中出现左心房自发性回声对比。
Cardiovasc Ultrasound. 2020 Aug 1;18(1):31. doi: 10.1186/s12947-020-00213-2.
8
The impact of risk score (CHADS2 versus CHA2DS2-VASc) on long-term outcomes after atrial fibrillation ablation.风险评分(CHADS2与CHA2DS2-VASc)对心房颤动消融术后长期预后的影响。
Heart Rhythm. 2015 Apr;12(4):681-6. doi: 10.1016/j.hrthm.2014.12.034. Epub 2014 Dec 26.
9
Predictive role of CHADS2 and CHA2DS2-VASc scores on stroke and thromboembolism in patients without atrial fibrillation: a meta-analysis.CHADS2和CHA2DS2-VASc评分对非房颤患者中风和血栓栓塞的预测作用:一项荟萃分析
Ann Med. 2016 Aug;48(5):367-75. doi: 10.1080/07853890.2016.1179390. Epub 2016 May 6.
10
Comparison between CHADS2 and CHA2DS2-VASc score for risk stratification of ischemic stroke in Japanese patients with non-valvular paroxysmal atrial fibrillation not receiving anticoagulant therapy.未接受抗凝治疗的日本非瓣膜性阵发性心房颤动患者缺血性卒中风险分层的CHADS2与CHA2DS2-VASc评分比较
Int Heart J. 2014;55(2):119-25. doi: 10.1536/ihj.13-242. Epub 2014 Mar 14.

引用本文的文献

1
Enhancing the evaluation of acute ischemic stroke risk in individuals with non-valvular atrial fibrillation by including laboratory indicators.通过纳入实验室指标来增强对非瓣膜性心房颤动个体的急性缺血性卒中风险的评估。
Sci Rep. 2024 Mar 21;14(1):6844. doi: 10.1038/s41598-024-57497-x.
2
Development and Validation of a New Nomogram Model for Predicting Acute Ischemic Stroke in Elderly Patients with Non-Valvular Atrial Fibrillation: A Single-Center Cross-Sectional Study.开发和验证一种新的列线图模型预测非瓣膜性心房颤动老年患者急性缺血性脑卒中:一项单中心横断面研究。
Clin Interv Aging. 2024 Jan 10;19:67-79. doi: 10.2147/CIA.S437065. eCollection 2024.
3

本文引用的文献

1
Corrigendum to: 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC.勘误:《2020年欧洲心脏病学会(ESC)与欧洲心胸外科学会(EACTS)合作制定的心房颤动诊断和管理指南》:欧洲心脏病学会(ESC)心房颤动诊断和管理特别工作组,由ESC的欧洲心律协会(EHRA)特别贡献制定。
Eur Heart J. 2021 Oct 21;42(40):4194. doi: 10.1093/eurheartj/ehab648.
2
Risk Factors Associated With Ischemic Stroke in Japanese Patients With Nonvalvular Atrial Fibrillation.与非瓣膜性心房颤动日本患者缺血性卒中相关的风险因素。
JAMA Netw Open. 2020 Apr 1;3(4):e202881. doi: 10.1001/jamanetworkopen.2020.2881.
3
Unveiling the Multifaceted Problems Associated with Dysrhythmia.
揭示心律失常相关的多方面问题。
Int J Mol Sci. 2023 Dec 23;25(1):263. doi: 10.3390/ijms25010263.
4
Challenges of Anticoagulant Therapy in Atrial Fibrillation-Focus on Gastrointestinal Bleeding.房颤抗凝治疗面临的挑战-关注胃肠道出血。
Int J Mol Sci. 2023 Apr 7;24(8):6879. doi: 10.3390/ijms24086879.
5
Ambient Air Pollution and Acute Ischemic Stroke-Effect Modification by Atrial Fibrillation.环境空气污染与急性缺血性卒中——心房颤动的效应修饰作用
J Clin Med. 2022 Sep 15;11(18):5429. doi: 10.3390/jcm11185429.
6
Role of New Potential Biomarkers in the Risk of Thromboembolism in Atrial Fibrillation.新型潜在生物标志物在心房颤动血栓栓塞风险中的作用
J Clin Med. 2022 Feb 9;11(4):915. doi: 10.3390/jcm11040915.
7
Pulmonary Vein Isolation Outcome Degree Is a New Score for Efficacy of Atrial Fibrillation Catheter Ablation.肺静脉隔离结局程度是心房颤动导管消融疗效的新评分。
J Clin Med. 2021 Dec 13;10(24):5827. doi: 10.3390/jcm10245827.
8
Retrospective Study of 1255 Non-Anticoagulated Patients with Nonvalvular Atrial Fibrillation to Determine the Risk of Ischemic Stroke Associated with Left Atrial Spontaneous Echo Contrast on Transesophageal Echocardiography.回顾性研究 1255 例非抗凝的非瓣膜性心房颤动患者,以确定经食管超声心动图检查左心房自发性回声对比与缺血性卒中相关的风险。
Med Sci Monit. 2021 Dec 11;27:e934795. doi: 10.12659/MSM.934795.
9
A Review of Biomarkers for Ischemic Stroke Evaluation in Patients With Non-valvular Atrial Fibrillation.非瓣膜性心房颤动患者缺血性卒中评估生物标志物综述
Front Cardiovasc Med. 2021 Jul 1;8:682538. doi: 10.3389/fcvm.2021.682538. eCollection 2021.
Association of relative wall thickness of left ventricle with incidence of thromboembolism in patients with non-valvular atrial fibrillation: The Fushimi AF Registry.非瓣膜性心房颤动患者左心室相对壁厚度与血栓栓塞发生率的关联:伏见房颤注册研究
Eur Heart J Qual Care Clin Outcomes. 2020 Oct 1;6(4):273-283. doi: 10.1093/ehjqcco/qcaa003.
4
Impact of hemoglobin concentration and platelet count on outcomes of patients with non-valvular atrial fibrillation: A subanalysis of the J-RHYTHM Registry.血红蛋白浓度和血小板计数对非瓣膜性心房颤动患者结局的影响:J-RHYTHM 登记研究的亚组分析。
Int J Cardiol. 2020 Mar 1;302:81-87. doi: 10.1016/j.ijcard.2019.11.127. Epub 2019 Nov 22.
5
Impact of Digitalis Use on Mortality in Japanese Patients With Non-Valvular Atrial Fibrillation - A Subanalysis of the J-RHYTHM Registry.洋地黄类药物使用对非瓣膜性心房颤动日本患者死亡率的影响 - J-RHYTHM 注册研究的亚组分析。
Circ J. 2019 Jul 25;83(8):1644-1652. doi: 10.1253/circj.CJ-19-0267. Epub 2019 Jun 19.
6
2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.2019年美国心脏协会/美国心脏病学会/心律学会对2014年美国心脏协会/美国心脏病学会/心律学会心房颤动患者管理指南的聚焦更新:美国心脏病学会/美国心脏协会临床实践指南工作组和心律学会的报告
J Am Coll Cardiol. 2019 Jul 9;74(1):104-132. doi: 10.1016/j.jacc.2019.01.011. Epub 2019 Jan 28.
7
Prevalence and Incidence of Atrial Fibrillation in the General Population Based on National Health Insurance Special Health Checkups - TAMA MED Project-AF.基于国民健康保险特定健康检查的一般人群中心房颤动的患病率和发生率 - TAMA MED 项目-AF。
Circ J. 2019 Feb 25;83(3):524-531. doi: 10.1253/circj.CJ-18-1038. Epub 2019 Jan 11.
8
Different determinants of vascular and nonvascular deaths in patients with atrial fibrillation: A SAKURA AF Registry substudy.心房颤动患者血管性和非血管性死亡的不同决定因素:SAKURA AF 注册研究的亚研究。
J Cardiol. 2019 Mar;73(3):210-217. doi: 10.1016/j.jjcc.2018.12.003. Epub 2018 Dec 24.
9
Management of atrial fibrillation for older people with frailty: a systematic review and meta-analysis.老年人衰弱相关心房颤动的管理:系统评价和荟萃分析。
Age Ageing. 2019 Mar 1;48(2):196-203. doi: 10.1093/ageing/afy180.
10
Progression From Paroxysmal to Sustained Atrial Fibrillation Is Associated With Increased Adverse Events.阵发性心房颤动向持续性心房颤动进展与不良事件增加相关。
Stroke. 2018 Oct;49(10):2301-2308. doi: 10.1161/STROKEAHA.118.021396.