Dy Christopher J, Peacock Kate, Olsen Margaret A, Ray Wilson Z, Brogan David M
Department of Orthopaedic Surgery, Division of Hand and Microsurgery, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8233, St. Louis, MO 63110 USA.
Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO USA.
HSS J. 2020 Dec;16(Suppl 2):339-343. doi: 10.1007/s11420-019-09741-8. Epub 2020 Jan 18.
Brachial plexus injury (BPI) is a life-altering event, and surgical treatment of BPI is costly ($66 million nationwide in 2006 alone). Despite the sizable costs associated with surgically treated BPI, the incidence of such cases in adults in the USA remains unknown.
QUESTIONS/PURPOSES: We sought to provide an estimate of the national incidence of surgically treated BPI in the USA and to determine whether changes have occurred over time.
We sought to identify privately insured adults ages 18 through 64 years who underwent BPI surgery between 2008 and 2014 in the IBM® MarketScan® Commercial Database. We then extrapolated those data to the same age group in the general population (all insurance types were considered), using data from the National Health Interview Survey and a study on the proportion of BPI surgery cases covered by private insurance to estimate the national incidence. We also used the Cochran-Armitage trend test to evaluate for statistically significant changes in BPI incidence over time in MarketScan private insurance data.
We identified 966 patients surgically treated for BPI in the MarketScan database in the study period. The average annual incidence of surgically treated BPI in this population of privately insured patients was 0.64 per 100,000 (range, 0.38 to 1.03). When extrapolated to all payers, the average annual incidence was 0.89 per 100,000 people (range, 0.53 to 1.47). In the MarketScan data, there was a statistically significant overall increase in the incidence of surgically treated BPI from 2008 through 2014 (0.47 per 100,000 to 1.03 per 100,000).
The estimated annual incidence of surgically treated BPI is 0.89 per 100,000 persons in the USA, and the incidence has increased over time. These findings can serve as a baseline for further studies of disease epidemiology and societal and financial impact.
臂丛神经损伤(BPI)是一种改变人生的事件,BPI的外科治疗成本高昂(仅2006年在全国范围内就达6600万美元)。尽管与接受外科治疗的BPI相关的成本巨大,但美国成年人中此类病例的发病率仍然未知。
问题/目的:我们试图估计美国接受外科治疗的BPI的全国发病率,并确定其随时间是否发生了变化。
我们试图在IBM® MarketScan®商业数据库中识别2008年至2014年间接受BPI手术的18至64岁的私人保险成年人。然后,我们使用来自国家健康访谈调查的数据以及一项关于私人保险涵盖的BPI手术病例比例的研究,将这些数据外推至一般人群中的同一年龄组(考虑所有保险类型),以估计全国发病率。我们还使用 Cochr an-Armitage趋势检验来评估MarketScan私人保险数据中BPI发病率随时间的统计学显著变化。
在研究期间,我们在MarketScan数据库中识别出966例接受BPI外科治疗的患者。在这群私人保险患者中,接受外科治疗的BPI的平均年发病率为每10万人0.64例(范围为0.38至1.03)。外推至所有支付方时,平均年发病率为每10万人0.89例(范围为0.53至1.47)。在MarketScan数据中,2008年至2014年期间接受外科治疗的BPI的发病率总体上有统计学显著增加(从每10万人0.