Yao Liang-Yu, Cong Rong, Meng Xiang-Hu, Song Ning-Hong
Department of Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
Kezhou People's Hospital Affiliated to Nanjing Medical University, Atush, Xinjiang 845350, China.
Zhonghua Nan Ke Xue. 2020 Nov;26(10):934-937.
MicroRNAs (miRNAs) are short non-coding RNAs consisting of approximately 19－23 nucleotides and involved in many pathological and physiological processes by regulating post-transcriptional gene expressions. ED is one of the common male sexual dysfunctions seriously affecting the patient's quality of life, for which there is currently a lack of effective treatments clinically. More and more experiments have demonstrated that miRNAs are involved in the pathological process of different types of ED. This article presents an overview of the progress in the studies of the pathogenic role of miRNAs in ED.
微小RNA（miRNA）是由大约19 - 23个核苷酸组成的短链非编码RNA，通过调节转录后基因表达参与许多病理和生理过程。勃起功能障碍（ED）是常见的男性性功能障碍之一，严重影响患者生活质量，目前临床上缺乏有效的治疗方法。越来越多的实验表明，miRNA参与了不同类型ED的病理过程。本文综述了miRNA在ED致病作用研究中的进展。
