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在 COVID-19 时代,行简化经导管主动脉瓣置换术且术后无并发症患者的当日出院安全性。

Safety of same-day discharge after uncomplicated, minimalist transcatheter aortic valve replacement in the COVID-19 era.

机构信息

Division of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.

Division of Cardiothoracic Surgery, Emory Structural Heart and Valve Center, Emory University Hospital Midtown, Atlanta, Georgia, USA.

出版信息

Catheter Cardiovasc Interv. 2021 Apr 1;97(5):940-947. doi: 10.1002/ccd.29453. Epub 2020 Dec 31.

Abstract

OBJECTIVES

We sought to evaluate the safety, efficacy and feasibility of same-day discharge after uncomplicated, minimalist TAVR.

BACKGROUND

At the start of the COVID-19 pandemic, we created a same-day discharge (SDD) pathway after conscious sedation, transfemoral (minimalist) TAVR to help minimize risk of viral transmission and conserve hospital resources. Studies support that next-day discharge (NDD) for carefully selected patients following minimalist TAVR is safe and feasible. There is a paucity of data regarding the safety of SDD after TAVR.

METHODS

In-hospital and 30 day outcomes of consecutive patients meeting pre-specified criteria for SDD after minimalist TAVR at our institution between March and July of 2020 were reviewed. Outcomes were compared to a NDD cohort from July 2018 through July 2020 that would have met SDD criteria. Primary endpoints were mortality, delayed pacemaker placement, stroke and cardiovascular readmission at 30 days.

RESULTS

Twenty nine patients were discharged via the SDD pathway after TAVR. 128 prior NDD patients were identified who met all criteria for SDD. The STS scores were similar between the two groups (SDD 2.6% ±1.5 vs. NDD 2.3% ± 1.2). There were no deaths at 30 days in either group. There was no significant difference in delayed pacemaker placement (SDD 0% vs. NDD 0.8%, p > .99) or cardiovascular readmission (SDD 0% vs. NDD 5.5%, p = .35) at 30 days.

CONCLUSIONS

Same day discharge following uncomplicated, minimalist TAVR in selected patients appears to be safe, achieving similar 30 day outcomes as a cohort of next day discharge patients.

摘要

目的

我们旨在评估在非复杂性、微创经导管主动脉瓣置换术(TAVR)后即刻出院的安全性、疗效和可行性。

背景

在 COVID-19 大流行开始时,我们创建了一种在全身麻醉下、经股动脉(微创)TAVR 后的即刻出院(SDD)途径,以帮助最大限度地降低病毒传播的风险并节约医院资源。研究支持,对于经过精心选择的患者,在微创 TAVR 后进行次日出院(NDD)是安全且可行的。关于 TAVR 后 SDD 的安全性,数据很少。

方法

回顾了 2020 年 3 月至 7 月期间,在我们机构中,符合微创 TAVR 后 SDD 预定义标准的连续患者的住院和 30 天结局。将这些结果与 2018 年 7 月至 2020 年 7 月期间的 NDD 队列进行比较,该队列本应符合 SDD 标准。主要终点是 30 天死亡率、延迟起搏器植入、卒中和心血管再入院。

结果

29 例患者通过 TAVR 后的 SDD 途径出院。确定了 128 例先前的 NDD 患者,他们符合 SDD 的所有标准。两组 STS 评分相似(SDD 2.6%±1.5 vs. NDD 2.3%±1.2)。两组在 30 天内均无死亡。延迟起搏器植入(SDD 0% vs. NDD 0.8%,p>0.99)或心血管再入院(SDD 0% vs. NDD 5.5%,p=0.35)在 30 天内无显著差异。

结论

在选定的患者中,在非复杂性、微创 TAVR 后即刻出院似乎是安全的,可获得与次日出院患者相似的 30 天结局。

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