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氧化石墨烯和二胺银氟化物与光动力疗法相比对树脂改性玻璃离子水门汀与脱矿牙本质的粘结完整性和微渗漏评分的影响。

Impact of graphene oxide and silver diamine fluoride in comparison to photodynamic therapy on bond integrity and microleakage scores of resin modified glass ionomer cement to demineralized dentin.

作者信息

Al-Qahtani Yasser M

机构信息

Consultant in Restorative Dentistry Department, Ministry of Health, Abha, Saudi Arabia.

出版信息

Photodiagnosis Photodyn Ther. 2021 Mar;33:102163. doi: 10.1016/j.pdpdt.2020.102163. Epub 2020 Dec 28.

DOI:10.1016/j.pdpdt.2020.102163
PMID:33383206
Abstract

AIM

To evaluate the impact of graphene oxide (GO) and silver diammine fluoride (SDF) in comparison to photodynamic therapy (PDT) on adhesive bond integrity and microleakage scores of resin-modified glass ionomer cement (RMGIC) to demineralized dentin.

METHODS

80 non-carious and atraumatic third molars were mounted inside the segments of polyvinyl pipes. Exposure, homogenization, and polishing of dentinal tubules was performed. 20 specimens were left unconditioned and classified a group 4. Exposure of acetic acid was done to 60 specimens and randomly allocated into 3 groups. Group 1 specimens were treated with 0.25 % GO; group 2 specimens were treated with 3.8 % SDF; and group 3 specimens were exposed to PDT. The bonding of all samples to RMGIC was performed by light curing and universal testing machine was utilized for testing shear bond strength (SBS). For failure modes, an optical microscope at 40x magnification was used to observe the debonded interfaces. For microleakage, all the specimens were submerged in 2% methylene blue for 1 day and observed under a digital microscope. The post hoc Tukey and analysis of variance (ANOVA) were used to examine SBS. A p-value of ≤0.05 was considered statistically significant.

RESULTS

Group 2 showed the highest bond strength (3.8 % SDF + RMGIC + DD - 15.27 ± 2.19 MPa). Groups 1 (0.25 % GO + RMGIC + DD - 14.11 ± 3.82) and 2 showed comparable results of SBS, which was significantly higher when compared with other research groups (p < 0.05). According to the post hoc Tukey test, the SBS scores of treatment groups exhibited statistically significant values as compared to the control group (p < 0.05). Group 2 samples showed the least microleakage mean score (0.8 ± 0.42), followed by group 1 specimens (1.02 ± 0.88). The comparable microleakage mean scores were demonstrated by the samples in group 1 and 2 (p < 0.01). According to one-way ANOVA, a significant difference was observed in microleakage scores among experimental groups (p < 0.01).

CONCLUSION

Improved bond strength and marginal microleakage scores were demonstrated by the demineralized dentin treated with 0.25 % graphene oxide and 3.8 % silver diamine fluoride when bonded to resin-modified glass ionomer cement. The application of methylene blue photosensitizer for photodynamic therapy undermined the adhesive bond strength applied on demineralized dentin.

摘要

目的

评估氧化石墨烯(GO)和氟化二氨银(SDF)与光动力疗法(PDT)相比,对树脂改性玻璃离子水门汀(RMGIC)与脱矿牙本质之间粘结完整性和微渗漏评分的影响。

方法

将80颗无龋且无外伤的第三磨牙安装在聚乙烯管段内。进行牙本质小管的暴露、均质化和抛光。20个样本不做处理,归为第4组。对60个样本进行醋酸暴露,并随机分为3组。第1组样本用0.25%的GO处理;第2组样本用3.8%的SDF处理;第3组样本接受PDT。所有样本与RMGIC的粘结通过光固化进行,并使用万能试验机测试剪切粘结强度(SBS)。对于失效模式,使用40倍放大倍数的光学显微镜观察脱粘界面。对于微渗漏,将所有样本浸泡在2%的亚甲蓝中1天,并在数码显微镜下观察。采用事后Tukey检验和方差分析(ANOVA)来检验SBS。p值≤0.05被认为具有统计学意义。

结果

第2组显示出最高的粘结强度(3.8% SDF + RMGIC + DD - 15.27±2.19MPa)。第1组(0.25% GO + RMGIC + DD - 14.11±3.82)和第2组的SBS结果相当,与其他研究组相比显著更高(p < 0.05)。根据事后Tukey检验,治疗组的SBS评分与对照组相比具有统计学意义(p < 0.

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