Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Division of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
Cancer Treat Res Commun. 2021;26:100294. doi: 10.1016/j.ctarc.2020.100294. Epub 2020 Dec 29.
patients with non-small-cell lung cancer (NSCLC) admitted to the intensive care unit have poor prognosis. There is limited data on cytotoxic chemotherapy in this setting. The standard of care for these patients is usually best supportive care.
60-year-old previously healthy female was admitted to the ICU with newly diagnosed mucinous adenocarcinoma of the lung. She received cisplatin and pemetrexed while intubated and mechanically ventilated. She was extubated a week later and discharged home after achieving an excellent radiographic and clinical response.
in select patients with NSCLC admitted to the ICU due to complications from their malignancy, a trial of cytotoxic chemotherapy may be reasonable. To our knowledge, this is the first case of mucinous NSCLC treated in the ICU.
入住重症监护病房的非小细胞肺癌 (NSCLC) 患者预后不良。在这种情况下，细胞毒性化疗的数据有限。这些患者的标准治疗通常是最佳支持治疗。
一位 60 岁的既往健康女性，因新诊断的肺黏液性腺癌被收入 ICU。她在插管和机械通气时接受了顺铂和培美曲塞治疗。一周后拔管，在获得出色的影像学和临床反应后出院回家。
在因恶性肿瘤并发症而入住 ICU 的 NSCLC 患者中，尝试细胞毒性化疗可能是合理的。据我们所知，这是首例在 ICU 治疗的黏液性 NSCLC 病例。
