Fundamental study of automatic cytoscreening for uterine cancer. V. Data analysis for imporvement of CYBEST.

The particles selected by CYBEST as "abnormal cells" at the stage of coarse scanning were examined by direct microscopy to determine whether they were actural cells or not. Approximately 20 to 30 per cent of these were cell clusters and/or clumped leukocytes and red cell or specks of dust. Such incidents interfered considerably with a precise cytologic assessment. To eliminate this problem by means of a software algorithm, experiments were carried out setting thresholds for cell feature values. When the values obtained by machine measurement exceeded the theshold values the particles concerned were automatically disregarded, as interfering indidents, at the state of the coarse scanning. The approach was found to have substantial value in the operation of CYBEST as a pescreening device.