Gerris J, Van Nueten J, Van Camp C, Gentens P, Van Dam P, Van Camp K
Department of Obstetrics and Gynecology, University Hospital of Antwerp, Belgium.
Eur J Obstet Gynecol Reprod Biol. 1988 Jan;27(1):33-41. doi: 10.1016/s0028-2243(88)80008-x.
Ninety-six couples, consulting for primary (n = 73) or secondary (n = 23) infertility, and thought to be infertile due to a varicocele in the husband associated with sperm abnormalities, were subjected to a follow-up study. Of these, 57 were surgically corrected and 39 were not, depending only on the patient's choice. All women were intensively treated where necessary. From our data we conclude that (1) fertility prognosis is significantly better in couples with secondary subfertility than in couples with primary subfertility, (2) surgical correction of varicocele in cases of secondary subfertility does not increase subsequent pregnancy rates, and (3) surgical correction of varicocele in cases of primary subfertility significantly increases subsequent pregnancy rates, since cumulative observed pregnancy rates are more than double the cumulative theoretically expected treatment-independent pregnancy rates.
96对因原发性（n = 73）或继发性（n = 23）不孕前来咨询的夫妇，被认为是由于丈夫精索静脉曲张伴精子异常而导致不孕，他们接受了一项随访研究。其中，57例接受了手术矫正，39例未接受手术矫正，这仅取决于患者的选择。所有女性在必要时都接受了强化治疗。根据我们的数据，我们得出以下结论：（1）继发性亚生育力夫妇的生育预后明显优于原发性亚生育力夫妇；（2）继发性亚生育力病例中精索静脉曲张的手术矫正不会提高后续妊娠率；（3）原发性亚生育力病例中精索静脉曲张的手术矫正显著提高了后续妊娠率，因为累积观察到的妊娠率是理论上预期的与治疗无关的累积妊娠率的两倍多。
