Lehtonen A, Viikari J
Acta Med Scand. 1977;202(3):179-81. doi: 10.1111/j.0954-6820.1977.tb16808.x.
In type II A hyperlipoproteinaemia, treatment with cholestyramine (12 g), calcium clofibrate (2 g) and a combination of calcium clofibrate and calcium carbonate (2 + 2 g) reduced the cholesterol concentration. The combination of calcium and clofibrate was at least as effective as cholestyramine. Calcium clofibrate decreased very low density and low density lipoprotein cholesterol, triglycerides and phospholipids, whereas no changes were found in high density lipoproteins. Cholestyramine decreased low density lipoprotein lipids.
在IIA型高脂蛋白血症中，使用消胆胺（12克）、安妥明钙（2克）以及安妥明钙与碳酸钙的组合（2 + 2克）进行治疗可降低胆固醇浓度。钙与安妥明的组合至少与消胆胺一样有效。安妥明钙可降低极低密度脂蛋白和低密度脂蛋白胆固醇、甘油三酯及磷脂，而高密度脂蛋白未发现变化。消胆胺可降低低密度脂蛋白脂质。
