EPIUnit-Instituto de Saúde Pública, Universidade Do Porto, Rua das Taipas, No. 135, 4050-600, Porto, Portugal.
Unidade de Saúde Pública-ACES Baixo Mondego, Figueira da Foz, Portugal.
AIDS Behav. 2021 Jun;25(6):1975-1983. doi: 10.1007/s10461-020-03127-2. Epub 2021 Jan 2.
We aimed to study the uptake of preexposure prophylaxis (PrEP) before and after its implementation in the Portuguese National Health Service (PNHS) among men who have sex with men (MSM). We studied 6164 participants in the Lisbon Cohort of MSM who participated between March 2014 and July 2019. 198 participants (3.2%) reported having recently used PrEP. Approximately one-third started PrEP after its implementation. PrEP uptake increased from 0.15% in 2014 to 5.36% in 2019. In their first use, 86 participants (70.5%) used it daily. How PrEP was obtained varied according to the timing of the first use: prescribed by a physician in Portugal (11.1% before vs 68.8% after implementation) and online (40.7% before vs 14.1% after). We observed an increase in the uptake and in the prescription by a physician, particularly after its implementation in the PNHS representing a change to a more equitable and safer way of using PrEP.
我们旨在研究在葡萄牙国家卫生服务（PNHS）实施之前和之后，男男性接触者（MSM）中使用暴露前预防（PrEP）的情况。我们研究了 2014 年 3 月至 2019 年 7 月间参与里斯本 MSM 队列的 6164 名参与者。198 名参与者（3.2%）报告最近使用过 PrEP。大约三分之一的人在实施后开始使用 PrEP。PrEP 的使用率从 2014 年的 0.15%上升到 2019 年的 5.36%。在首次使用时，86 名参与者（70.5%）每天使用。首次使用 PrEP 的方式因时间而异：在葡萄牙由医生开具处方（实施前为 11.1%，实施后为 68.8%）和在线（实施前为 40.7%，实施后为 14.1%）。我们观察到 PrEP 的使用率和医生开具处方的比例均有所增加，尤其是在 PNHS 实施之后，这代表了一种更加公平和安全的使用 PrEP 的方式的转变。
