粪菌移植治疗膜性肾病。
Fecal microbiota transplantation for membranous nephropathy.
机构信息
Department of Gastroenterology and Hepatology, The First Medical Center, Chinese PLA General Hospital, Beijing, 100853, China.
Medical College of Nankai University, Tianjin, 300071, China.
出版信息
CEN Case Rep. 2021 May;10(2):261-264. doi: 10.1007/s13730-020-00560-z. Epub 2021 Jan 2.
Abstract
Membranous nephropathy is a pathological type of nephrotic syndrome. Current treatments including supportive therapy, corticosteroids, immunosuppressive agents are not effective for all patients. New therapies are needed to treat the disease safely and effectively. Gut microbiota may contribute to the pathogenesis of this disease. Fecal microbiota transplantation (FMT) has made achievements in many diseases. Here, we report a case in which FMT is used to treat a patient with membranous nephropathy and chronic diarrhea, whose symptoms ameliorated and renal function improved.
摘要
膜性肾病是肾病综合征的一种病理类型。目前的治疗方法包括支持治疗、皮质类固醇、免疫抑制剂等，但并非对所有患者都有效。需要新的治疗方法来安全有效地治疗这种疾病。肠道微生物群可能有助于这种疾病的发病机制。粪便微生物群移植（FMT）在许多疾病中已取得成效。在这里，我们报告了一例使用 FMT 治疗膜性肾病和慢性腹泻患者的病例，其症状得到改善，肾功能得到改善。
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