Department of Radiology, Fukushima Medical University Hospital, Fukushima, Japan.
Healthcare IT Software Development Department, Healthcare IT Development Center, Healthcare IT Division, Canon Medical Systems Corporation, Tochigi, Japan.
Radiol Phys Technol. 2021 Mar;14(1):50-56. doi: 10.1007/s12194-020-00601-3. Epub 2021 Jan 2.
Myocardial T1 mapping is a useful technique for the diagnosis of diffuse fibrosis. Although modified look-locker inversion recovery is a widely used T1 mapping method, variation in T1 values has been reported. Non-uniform T1 maps may hinder differentiation between healthy and diseased myocardial tissue. The purpose of this study was to investigate the uniformity of T1 mapping using polarity corrected inversion time preparation (PC TI prep) in a myocardial phantom and healthy volunteers. The myocardial phantom was scanned between polyvinyl alcohol (PVA) and air. T1 values were measured using inversion recovery fast spin-echo (IR-FSE) and PC TI prep in areas adjacent to PVA and air. For the volunteer study, the short-axis plane was imaged using the PC TI prep to compare T1 values in the myocardium of the septal and lateral walls. The T1 value of the phantom using the IR-FSE was not significantly different in the area between PVA and air, whereas the T1 value using the PC TI prep in the air area was significantly lower than that in the PVA area. T1 mapping of the healthy myocardium exhibited no significant difference between the septal and lateral walls. The T1 value using the PC TI prep in the air area was 6.3% lower than that using IR-FSE. In this study, T1 mapping using the PC TI prep exhibited high uniformity of T1 values.
心肌 T1 映射是一种用于诊断弥漫性纤维化的有用技术。尽管改良 Look-Locker 反转恢复是一种广泛使用的 T1 映射方法，但已经报道了 T1 值的变化。非均匀 T1 图谱可能会阻碍健康和患病心肌组织之间的区分。本研究旨在研究心肌仿体和健康志愿者中使用极性校正反转时间准备（PC TI prep）的 T1 映射均匀性。心肌仿体在聚乙烯醇（PVA）和空气之间进行扫描。使用反转恢复快速自旋回波（IR-FSE）和 PC TI prep 在靠近 PVA 和空气的区域测量 T1 值。对于志愿者研究，使用 PC TI prep 对短轴平面进行成像，以比较间隔壁和侧壁心肌的 T1 值。IR-FSE 测量的仿体 T1 值在 PVA 和空气之间的区域没有显着差异，而 PC TI prep 在空气区域的 T1 值明显低于 PVA 区域。健康心肌的 T1 映射在间隔壁和侧壁之间没有显着差异。PC TI prep 在空气区域的 T1 值比 IR-FSE 低 6.3%。在这项研究中，使用 PC TI prep 的 T1 映射表现出 T1 值的高度均匀性。
