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隐睾扭转的多中心回顾:呼吁早期处理

A multicenter review of undescended testis torsion: A plea for early management.

作者信息

Dupond-Athénor Adrien, Peycelon Matthieu, Abbo Olivier, Rod Julien, Haraux Elodie, Scalabre Aurélien, Arnaud Alexis, Guérin Florent, Irtan Sabine

机构信息

Sorbonne Université, Department of Pediatric Surgery, APHP Hôpital Armand Trousseau, 26 Avenue du Dr Arnold Netter, 75012, Paris, France.

Department of Pediatric Surgery and Urology, APHP Hôpital Universitaire Robert-Debré, Centres de Référence Maladies Rares, Maladies Endocriniennes Rares de la Croissance (CRMERC), Université de Paris, 48 Bd Sérurier, 75019, Paris, France; Sorbonne Université, INSERM UMR_S933, Maladies Génétiques d'expression Pédiatrique, APHP, Hôpital Armand Trousseau, 26 Avenue du Dr Arnold Netter, 75012, Paris, France.

出版信息

J Pediatr Urol. 2021 Apr;17(2):191.e1-191.e6. doi: 10.1016/j.jpurol.2020.12.004. Epub 2020 Dec 8.

Abstract

INTRODUCTION

Torsion of an undescended testis (UT) is a surgical emergency, difficult to diagnose, whose prognosis depends on a quick management.

AIM OF THE STUDY

To evaluate the management and outcome of these patients.

STUDY DESIGN

We retrospectively analyzed all cases of UT torsion operated in nine French hospitals between 1997 and 2017. We divided patients in two groups: patients referred less than 6 h after the onset of symptoms (group A) or more than 6 h (group B).

MAIN RESULTS

We collected 60 cases (17 in group A and 43 in group B). Median age was 2.2 years [IQR = 0.7-7.8] (2.3 y in group A and 2 y in group B, p = 0.76). Eleven patients (10 in group B) had neurological disorders (p = 0.15). The main reason for absence of UT treatment was the absence of surgical consultation in a normal delay (n = 44, 73%). Symptoms were pain (n = 58, 97%), inguinal mass (n = 55, 92%) and vomiting (n = 16, 27%). An inguinal mass with no palpable testis in the ipsilateral hemiscrotum was seen in 55 patients (92%). An ultrasound scan performed in 27 patients led to the diagnosis in 16 patients (59%). At surgery, an orchiectomy was performed in 4 patients (23%) of group A and 24 patients (56%) of group B (p = 0.04). After a median follow-up of 11 months [IQR = 4-23], 11 patients of group A (65%) and 7 patients of group B (16%) had a clinically normal testis (p = 0.03). The salvage rate among patients with conservative treatment was 85% for group A and 37% for group B (p = 0.01).

DISCUSSION

Our study reveals that although UT torsion is an emergency, 72% of patients are referred more than 6 h after the onset of symptoms. We mostly found classic clinical presentation of UT torsion: a painful inguinal mass with an empty ipsilateral scrotum. Ultrasound was performed in half cases, and even if the result was not significant, it still seemed to be associated with a higher rate of orchiectomy especially in group B because of the delay in care. However, when ultrasound was realized early, it led to diagnosis in all cases. This dilemma poses the problem of the role of imaging in diagnostic management.

CONCLUSIONS

Early clinical diagnosis in front of a painful inguinal mass with an empty scrotum is essential to improve the salvage rate of testis in UT torsion. Early management of UT should have avoided 68% of testis loss.

摘要

引言

隐睾扭转是一种外科急症,诊断困难,其预后取决于能否迅速处理。

研究目的

评估这些患者的治疗及预后情况。

研究设计

我们回顾性分析了1997年至2017年间在法国9家医院接受手术的所有隐睾扭转病例。我们将患者分为两组:症状出现后6小时内就诊的患者(A组)和症状出现后6小时以上就诊的患者(B组)。

主要结果

我们收集了60例病例(A组17例,B组43例)。中位年龄为2.2岁[四分位间距=0.7 - 7.8](A组2.3岁,B组2岁,p = 0.76)。11例患者(B组10例)患有神经疾病(p = 0.15)。未进行隐睾治疗的主要原因是未在正常时间内进行外科会诊(n = 44,73%)。症状包括疼痛(n = 58,97%)、腹股沟肿块(n = 55,92%)和呕吐(n = 16,27%)。55例患者(92%)在同侧阴囊内可触及无睾丸的腹股沟肿块。27例患者进行了超声检查,其中16例(59%)得以确诊。手术中,A组4例患者(23%)和B组24例患者(56%)进行了睾丸切除术(p = 0.04)。中位随访11个月[四分位间距=4 - 23]后,A组11例患者(65%)和B组7例患者(16%)的患侧睾丸临床检查正常(p = 0.03)。保守治疗患者中,A组的挽救率为85%,B组为37%(p = 0.01)。

讨论

我们的研究表明,尽管隐睾扭转是一种急症,但72%的患者在症状出现后6小时以上才就诊。我们大多发现了隐睾扭转的典型临床表现:疼痛的腹股沟肿块且同侧阴囊空虚。半数病例进行了超声检查,即便结果不显著,但似乎仍与较高的睾丸切除率相关,尤其是在B组,这是由于延误了治疗。然而,若早期进行超声检查,所有病例均可确诊。这一困境引发了影像学在诊断管理中作用的问题。

结论

对于疼痛的腹股沟肿块且阴囊空虚的情况,早期临床诊断对于提高隐睾扭转患者睾丸的挽救率至关重要。隐睾的早期处理本可避免68%的睾丸丧失。

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