Wysenbeek Y S, Loya N, Ben Sira I, Ophir I, Ben Shaul Y
Department of Ophthalmology, Beilinson Medical Center, Petah Tikva, Israel.
Invest Ophthalmol Vis Sci. 1988 Feb;29(2):194-9.
The effect of sodium hyaluronate (NaHa) 1% and 0.1% was studied on 14-day chick embryo corneal epithelium by scanning electron microscopy. It was found that NaHa 1% or 0.1% had no toxic effects on the chick corneal epithelium and the normal architecture of the cells and the morphology of the microvilli was well preserved. A combination of NaHa 0.1% and benzalkonium chloride (BAK) 0.01% reduced the toxic effect of BAK on the surface corneal epithelium. NaHa 0.1% provided a better protection of the corneal epithelium against dryness than hydroxyethylcellulose (HEC) 0.1% or phosphate buffer saline (PBS).
通过扫描电子显微镜研究了1%和0.1%的透明质酸钠（NaHa）对14日龄鸡胚角膜上皮的影响。发现1%或0.1%的NaHa对鸡角膜上皮无毒性作用，细胞的正常结构和微绒毛的形态得到良好保存。0.1%的NaHa与0.01%的苯扎氯铵（BAK）联合使用可降低BAK对角膜表面上皮的毒性作用。0.1%的NaHa比0.1%的羟乙基纤维素（HEC）或磷酸盐缓冲盐水（PBS）能更好地保护角膜上皮免受干燥影响。
