我们是否应该继续建议家庭在高危婴儿中使用水解配方奶粉作为预防过敏的一种方法？
Should we continue to counsel families to use hydrolyzed formulas as a means of allergy prevention in high-risk infants?
作者信息
Burke Megan, Chan Edmond S, Abrams Elissa M
机构信息
Division of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia.
Section of Allergy and Clinical Immunology, Department of Pediatrics, University of Manitoba, Winnipeg, Manitoba.
出版信息
Paediatr Child Health. 2020 Mar;25(2):79-81. doi: 10.1093/pch/pxz098. Epub 2019 Jul 29.
The prevalence of food allergy in North America is high, and has increased over time. As a result, focus has shifted from treatment to allergy prevention. Previous studies have suggested that hydrolyzed formula may prevent atopic dermatitis in high-risk infants. As a result, multiple international guidelines including the Canadian Paediatric Society (CPS) position statement on allergy prevention recommend the use of hydrolyzed formula as a means of allergy prevention in mothers who are not breastfeeding or using donor breastmilk. However, a recent systematic review has not supported an association between use of hydrolyzed formula and allergy prevention. In addition, studies are emerging supporting the use of early and regular cow's milk formula as a means of cow's milk allergy prevention.
北美食物过敏的患病率很高，且随时间推移有所增加。因此，重点已从治疗转向过敏预防。先前的研究表明，水解配方奶粉可能预防高危婴儿患特应性皮炎。因此，包括加拿大儿科学会（CPS）关于过敏预防的立场声明在内的多项国际指南建议，对于不进行母乳喂养或不使用捐赠母乳的母亲，使用水解配方奶粉作为预防过敏的一种方法。然而，最近的一项系统评价并不支持水解配方奶粉的使用与过敏预防之间存在关联。此外，越来越多的研究支持将早期和常规的牛奶配方奶粉作为预防牛奶过敏的一种方法。
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