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高危婴儿的饮食暴露与过敏预防:与加拿大过敏与临床免疫学会的联合声明

Dietary exposures and allergy prevention in high-risk infants: A joint statement with the Canadian Society of Allergy and Clinical Immunology.

作者信息

Chan Edmond S, Cummings Carl

出版信息

Paediatr Child Health. 2013 Dec;18(10):545-54. doi: 10.1093/pch/18.10.545.

DOI:10.1093/pch/18.10.545
PMID:24497783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3907352/
Abstract

Allergic conditions in children are a prevalent health concern in Canada. The burden of disease and the societal costs of proper diagnosis and management are considerable, making the primary prevention of allergic conditions a desirable health care objective. This position statement reviews current evidence on dietary exposures and allergy prevention in infants at high risk for developing allergic conditions. It revisits previous dietary recommendations for pregnancy, breastfeeding and formula feeding, and provides an approach for introducing solid foods to high-risk infants. While there is no evidence that delaying the introduction of any specific food beyond six months of age helps to prevent allergy, the protective effect of early introduction of potentially allergenic foods (at four to six months of age) remains under investigation. Recent research appears to suggest that regularly ingesting a new, potentially allergenic food may be as important as when that food is first introduced.

摘要

儿童过敏疾病是加拿大普遍存在的健康问题。疾病负担以及正确诊断和管理的社会成本相当可观,这使得过敏疾病的一级预防成为一个理想的医疗保健目标。本立场声明回顾了有关高危婴儿饮食暴露与过敏预防的现有证据。它重新审视了先前关于孕期、母乳喂养和配方奶喂养的饮食建议,并提供了一种向高危婴儿引入固体食物的方法。虽然没有证据表明在六个月龄后延迟引入任何特定食物有助于预防过敏,但早期引入潜在致敏食物(四至六个月龄)的保护作用仍在研究中。最近的研究似乎表明,经常摄入一种新的潜在致敏食物可能与首次引入该食物的时间同样重要。

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本文引用的文献

1
Primary prevention of allergic disease through nutritional interventions.通过营养干预进行过敏性疾病的一级预防。
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Timing of infant feeding in relation to childhood asthma and allergic diseases.婴儿喂养时间与儿童哮喘和过敏性疾病的关系。
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Timing of the introduction of complementary foods in infancy: a randomized controlled trial.婴儿期引入补充食品的时间:一项随机对照试验。
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8
Maternal dietary antigen avoidance during pregnancy or lactation, or both, for preventing or treating atopic disease in the child.孕期或哺乳期或二者期间避免母体膳食抗原以预防或治疗儿童过敏性疾病。
Cochrane Database Syst Rev. 2012 Sep 12;2012(9):CD000133. doi: 10.1002/14651858.CD000133.pub3.
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Overall prevalence of self-reported food allergy in Canada.加拿大自我报告的食物过敏总体患病率。
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FDA's health claim review: whey-protein partially hydrolyzed infant formula and atopic dermatitis.FDA 的健康声称审查:乳清蛋白部分水解婴儿配方和特应性皮炎。
Pediatrics. 2012 Aug;130(2):e408-14. doi: 10.1542/peds.2012-0333. Epub 2012 Jul 9.