Shirasugi Nozomu, Horiguchi Sadaaki, Tanaka Takamitsu, Shirato Hiroyuki, Ono Hisako, Kawasugi Kazuo
Varicose Vein Center and Department of Vascular Surgery, Yokohama Asahi Chuo General Hospital, Yokohama, Kanagawa, Japan.
Varicose Vein Center, Aisei Hospital, Tokyo, Japan.
Ann Vasc Dis. 2020 Dec 25;13(4):461-464. doi: 10.3400/avd.cr.20-00137.
Factor XII (FXII) deficiency is a rare coagulation disorder, and its potential relationship with venous thrombosis was reported. Here we present a case of a 67-year-old woman with FXII deficiency who successfully underwent endovenous thermal ablation (ETA) for primary varicose vein due to the incompetent great saphenous vein (GSV). The FXII deficiency was revealed through preoperative examinations, and the patient underwent ETA as a day surgery. For prophylaxis of thrombosis, she received compression therapy alone. Her postoperative course was uneventful, without any kind of thrombosis. In the presence of FXII deficiency, ETA could be safely performed.
因子 XII（FXII）缺乏症是一种罕见的凝血障碍疾病，其与静脉血栓形成的潜在关系已有报道。在此，我们报告一例 67 岁患有 FXII 缺乏症的女性患者，因大隐静脉（GSV）功能不全成功接受了原发性静脉曲张的腔内热消融术（ETA）。术前检查发现该患者存在 FXII 缺乏症，患者作为日间手术接受了 ETA。为预防血栓形成，她仅接受了压迫治疗。她的术后过程平稳，未出现任何类型的血栓形成。在存在 FXII 缺乏症的情况下，ETA 可以安全进行。
