Department of Renal Medicine, Singapore General Hospital, Outram Rd, Singapore, 169608, Singapore.
Division of Pathology, Singapore General Hospital, Singapore, Singapore.
CEN Case Rep. 2021 May;10(2):273-280. doi: 10.1007/s13730-020-00546-x. Epub 2021 Jan 3.
Nodular glomerulosclerosis, typically diagnosed in patients with diabetes mellitus, has been reported in native kidneys of pre-diabetic patients but similar cases in kidney transplant recipients are lacking. We describe a case of nodular glomerulosclerosis in a kidney transplant recipient who had not been found to be diabetic despite regular screening and discuss the implications for the pathogenesis and diagnosis of nodular glomerulosclerosis and screening of post-transplant diabetes mellitus.
结节性肾小球硬化症,通常在糖尿病患者中诊断,已在非糖尿病患者的原肾中报告,但在肾移植受者中缺乏类似病例。我们描述了一例肾移植受者的结节性肾小球硬化症病例,尽管进行了常规筛查,但未发现该患者患有糖尿病,并讨论了结节性肾小球硬化症发病机制和诊断以及移植后糖尿病筛查的意义。