Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford.
Eur Heart J. 2021 Mar 1;42(9):948-950. doi: 10.1093/eurheartj/ehaa1059.
Graphical abstract Establishment of an autoreactive B cell memory after myocardial infarction: a working hypothesis. The demise of cardiac cells leads to the release of cryptoantigens that induce a humoral immune response that leads to accumulation of immunoglobulins in plaques and eventually amplifies atherogenesis at remote sites.
图形摘要 心肌梗死后自身反应性 B 细胞记忆的建立：一个工作假说。心肌细胞的死亡导致隐匿抗原的释放，引发体液免疫反应，导致免疫球蛋白在斑块中积累，并最终在远处部位放大动脉粥样硬化形成。
