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外耳道上皮样肉瘤：罕见部位的罕见肿瘤，并简要概述文献。

Epithelioid Sarcoma of the External Auditory Canal: An Uncommon Tumor at an Unusual Site and a Brief Overview of the Literature.

机构信息

Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.

Department of Otolaryngology, National University Health System, Singapore, Singapore.

出版信息

Head Neck Pathol. 2021 Dec;15(4):1328-1334. doi: 10.1007/s12105-020-01275-4. Epub 2021 Jan 4.

DOI:10.1007/s12105-020-01275-4
PMID:33394376
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8633210/
Abstract

We present a case (41 years old pregnant female) with epithelioid sarcoma arising in the left external auditory canal. On immunohistochemistry, the tumor cell diffusely expressed cytokeratins and showed patchy expression of ERG and CD34. The neoplastic cells demonstrated uniform loss of INI1-expression. Epithelioid sarcoma arising in the external auditory canal is rare. Awareness that ES may rarely arise at unusual sites is of critical importance in order to apply a broad enough panel in the immunohistochemical study, so a misdiagnosis of carcinoma can be avoided.

摘要

我们报告 1 例（41 岁孕妇）发生于左侧外耳道的上皮样肉瘤。免疫组化结果示肿瘤细胞弥漫表达细胞角蛋白，局灶表达 ERG 和 CD34。肿瘤细胞均表现为 INI1 表达缺失。发生于外耳道的上皮样肉瘤罕见。了解上皮样肉瘤可能罕见地发生于不常见部位非常重要，以便在免疫组化研究中应用足够广泛的抗体谱，从而避免误诊为癌。