BD Biosciences, San Jose, California, USA.
NYU Langone Medical Center, New York, New York, USA.
Cytometry B Clin Cytom. 2021 Jan;100(1):33-41. doi: 10.1002/cyto.b.21988. Epub 2021 Jan 4.
Over a remarkably short period of time, a great deal of knowledge about severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection has been acquired, through the focused and cooperative effort of the international scientific community. Much has become known about how the immune response is coordinated to fight infection, and how it becomes dysregulated in severe disease. In this review, we take an in-depth look at the many immune features associated with the host response to SARS-CoV2, as well as those that appear to mark severe disease.
在相当短的时间内，通过国际科学界的集中协作，人们对严重急性呼吸综合征冠状病毒 2（SARS-CoV2）感染有了大量的了解。人们已经了解了免疫反应是如何协调来对抗感染的，以及在严重疾病中它是如何失调的。在这篇综述中，我们深入研究了与宿主对 SARS-CoV2 反应相关的许多免疫特征，以及那些似乎标志着严重疾病的免疫特征。
