Allergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Curr Opin Allergy Clin Immunol. 2021 Apr 1;21(2):188-194. doi: 10.1097/ACI.0000000000000721.
To underline the main characteristics of the non-Immunoglobulin E (IgE)-mediated food allergies (food protein-induced allergic proctocolitis food protein-induced enteropathy and food protein-induced enterocolitis syndrome ), which are common diseases in primary care and in allergy and gastroenterology specialty practices evaluating children.
Non-IgE-mediated food allergies comprise a spectrum of diseases with peculiar features affecting infants and young children. The most prominent features of these diseases are symptoms that affect mainly the gastrointestinal tract.
It is of paramount importance to provide the clinicians with the tools for non-IgE-mediated food allergy recognition in clinical practice to avoid the misdiagnosis with unnecessary laboratory tests and detrimental treatments.
强调非免疫球蛋白 E(IgE)介导的食物过敏(食物蛋白诱导的直肠结肠炎、食物蛋白诱导的肠病和食物蛋白诱导的肠病综合征)的主要特征,这些疾病在初级保健和过敏及胃肠病专科实践中均常见于评估儿童。
非 IgE 介导的食物过敏包括一系列具有特殊特征的疾病,主要影响婴儿和幼儿。这些疾病的最突出特征是主要影响胃肠道的症状。
在临床实践中为临床医生提供识别非 IgE 介导的食物过敏的工具至关重要,以避免因不必要的实验室检查和有害治疗而误诊。