Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Department of Ophthalmology, Inha University Hospital, Inha University School of Medicine, Incheon , Republic of Korea; and.
Retina. 2021 Aug 1;41(8):1652-1659. doi: 10.1097/IAE.0000000000003087.
To investigate the types of intraretinal cysts that are associated with epiretinal membranes and to evaluate the effects of each type of intraretinal cyst on postoperative outcomes.
Retrospective, cross-sectional study design. Patients who underwent preoperative fluorescent angiography and epiretinal membrane surgery from February 2014 to May 2019 were included. Intraretinal cysts were subdivided into cystoid macular edema with angiographic leakage and microcystic macular edema (MME) without angiographic leakage.
A total of 100 eyes from 100 patients were enrolled. Intraretinal cysts were present in 54 (54.0%) eyes before surgery, of which 27 (27.0%) eyes showed MME, 18 (18.0%) eyes showed cystoid macular edema, and 9 (9.0%) eyes showed cystoid macular edema and MME. After surgery, the number of eyes with cystoid macular edema decreased significantly (P < 0.001), whereas the number of eyes with MME did not (P = 0.302). Absence of preoperative MME, poorer initial visual acuity, increased central foveal thickness, and intact ellipsoidal zone were associated with favorable visual recovery (P = 0.035, 0.033, 0.018, and 0.035, respectively).
Microcystic macular edema associated with epiretinal membranes was a poor prognostic factor for epiretinal membrane surgery. The persistent existence of MME after surgery affirms related chronic structural changes. Further studies should investigate whether earlier surgical intervention (possibly before the development of MME) benefits visual outcomes.
研究与视网膜前膜相关的视网膜内囊的类型，并评估每种类型的视网膜内囊对术后结果的影响。
回顾性、横断面研究设计。纳入 2014 年 2 月至 2019 年 5 月接受术前荧光血管造影和视网膜前膜手术的患者。将视网膜内囊分为伴有血管造影渗漏的囊样黄斑水肿和无血管造影渗漏的微囊样黄斑水肿（MME）。
共纳入 100 例 100 只眼的患者。术前有视网膜内囊 54 只眼（54.0%），其中 27 只眼（27.0%）为 MME，18 只眼（18.0%）为囊样黄斑水肿，9 只眼（9.0%）为囊样黄斑水肿和 MME。手术后，伴有囊样黄斑水肿的眼数明显减少（P < 0.001），而伴有 MME 的眼数没有减少（P = 0.302）。术前无 MME、初始视力较差、中央视网膜厚度增加和椭圆体带完整与良好的视力恢复相关（P = 0.035、0.033、0.018 和 0.035）。
与视网膜前膜相关的微囊样黄斑水肿是视网膜前膜手术预后不良的因素。手术后 MME 的持续存在证实了相关的慢性结构变化。进一步的研究应探讨早期手术干预（可能在 MME 发生之前）是否有益于视力结果。
