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如何识别创伤性脑损伤患者的脑疝 - 神经外科医生的观点。

How do we identify the crashing traumatic brain injury patient - the neurosurgeon's view.

机构信息

Neurocenter, Department of Neurosurgery and Turku Brain Injury Center, Turku University Hospital and University of Turku, Turku.

Department of Neurosurgery, Helsinki University Hospital and University of Helsinki, Helsinki.

出版信息

Curr Opin Crit Care. 2021 Apr 1;27(2):87-94. doi: 10.1097/MCC.0000000000000799.

DOI:10.1097/MCC.0000000000000799
PMID:33395087
Abstract

PURPOSE OF REVIEW

To provide an overview on recent advances in the field of assessment and monitoring of patients with severe traumatic brain injury (sTBI) in neurocritical care from a neurosurgical point of view.

RECENT FINDINGS

In high-income countries, monitoring of patients with sTBI heavily relies on multimodal neurocritical parameters, nonetheless clinical assessment still has a solid role in decision-making. There are guidelines and consensus-based treatment algorithms that can be employed in both absence and presence of multimodal monitoring in the management of patients with sTBI. Additionally, novel dynamic monitoring options and machine learning-based prognostic models are introduced. Currently, the acute management and treatment of secondary injury/insults is focused on dealing with the objective evident pathology. An ongoing paradigm shift is emerging towards more proactive treatment of neuroworsening as soon as premonitory signs of deterioration are detected.

SUMMARY

Based on the current evidence, serial clinical assessment, neuroimaging, intracranial and cerebral perfusion pressure and brain tissue oxygen monitoring are key components of sTBI care. Clinical assessment has a crucial role in identifying the crashing patient with sTBI, especially from a neurosurgical standpoint. Multimodal monitoring and clinical assessment should be seen as complementary evaluation methods that support one another.

摘要

目的综述

从神经外科角度出发,提供神经重症监护中严重创伤性脑损伤(sTBI)患者评估和监测的最新进展概述。

最近的发现

在高收入国家,sTBI 患者的监测严重依赖于多模态神经重症监护参数,但临床评估在决策中仍具有重要作用。在没有和存在多模态监测的情况下,都有指南和基于共识的治疗算法可用于 sTBI 患者的管理。此外,还引入了新的动态监测选项和基于机器学习的预后模型。目前,继发性损伤/损伤的急性处理和治疗侧重于处理客观明显的病理。正在出现一种向更早地治疗神经恶化的治疗模式转变,一旦出现恶化的先兆迹象,就会进行治疗。

总结

基于目前的证据,连续的临床评估、神经影像学、颅内和脑灌注压以及脑组织氧监测是 sTBI 护理的关键组成部分。临床评估在识别 sTBI 患者,特别是从神经外科角度来看,具有至关重要的作用。多模态监测和临床评估应被视为互补的评估方法,相互支持。

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Acta Neurochir (Wien). 2023 Nov;165(11):3217-3227. doi: 10.1007/s00701-023-05797-y. Epub 2023 Sep 25.
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Neuroworsening in the Emergency Department Is a Predictor of Traumatic Brain Injury Intervention and Outcome: A TRACK-TBI Pilot Study.急诊科神经功能恶化是创伤性脑损伤干预及预后的预测指标:TRACK-TBI试点研究
J Clin Med. 2023 Mar 3;12(5):2024. doi: 10.3390/jcm12052024.
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Assessing the relationship between the cerebral metabolic rate of oxygen and the oxidation state of cytochrome-c-oxidase.
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Neurophotonics. 2022 Jul;9(3):035001. doi: 10.1117/1.NPh.9.3.035001. Epub 2022 Jul 20.