Division of Infectious Diseases, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.
Division of Allergy and Clinical Immunology, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.
J Mycol Med. 2021 Mar;31(1):101106. doi: 10.1016/j.mycmed.2020.101106. Epub 2021 Jan 1.
Invasive Rasamsonia spp. infections are rare and usually associated with chronic granulomatous disease (CGD). We present a case of pulmonary and possible cerebral infection due to Rasamsonia argillacea in a girl with CGD receiving no primary antifungal prophylaxis. There was a fatal outcome despite the combination of antifungal therapy and surgical interventions. We also conducted a literature review on reported invasive Rasamsonia spp. infections in the setting of CGD.
侵袭性拉沙氏菌属感染较为罕见，通常与慢性肉芽肿病（CGD）有关。我们报告了一例 CGD 女孩发生肺和可能的脑感染，该女孩未接受初级抗真菌预防。尽管联合使用抗真菌治疗和手术干预，仍导致了致命结局。我们还对 CGD 背景下报告的侵袭性拉沙氏菌属感染进行了文献复习。
