Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
Eur J Radiol. 2021 Feb;135:109489. doi: 10.1016/j.ejrad.2020.109489. Epub 2020 Dec 24.
T1rho imaging is a new quantitative MRI sequence for head and neck cancer and the repeatability for this region is unknown. This study aimed to evaluate the repeatability of quantitative T1rho imaging in the head and neck.
T1rho imaging of the head and neck was prospectively performed in 15 healthy participants on three occasions. Scan 1 and 2 were performed with a time interval of 30 minutes (intra-session) and scan 3 was performed 14 days later (inter-session). T1rho values for normal tissues (parotid glands, palatine tonsils, pterygoid muscles, and tongue) were obtained on each scan. Intra-class coefficients (ICCs), within-subject coefficient of variances (wCoVs), and repeatability coefficient (RCs) of the intra-session scan (scan 1 vs 2) and inter-session scan (scan 1 vs 3) for the normal tissues were calculated.
The ICCs of T1rho values for normal tissues were almost perfect (0.83-0.97) for intra-session scans and were substantial (0.71-0.80) for inter-session scans. The wCoVs showed a small range (2.46%-3.30%) for intra-session scans, and slightly greater range (3.27%-6.51%) for inter-session scan. The greatest and lowest wCoVs of T1rho were found in the parotid gland and muscles, respectively. The T1rho RCs varied for all tissues between intra- and inter- sessions, and the greatest RC of 10.07 msec was observed for parotid gland on inter-session scan.
T1rho imaging is a repeatable quantitative MRI sequence in the head and neck but variances of T1rho values among tissues should be take into account during analysis.
T1rho 成像是一种新的头部和颈部癌症定量 MRI 序列，其在该区域的可重复性尚不清楚。本研究旨在评估头部和颈部定量 T1rho 成像的可重复性。
前瞻性地对 15 名健康参与者的头部和颈部进行 T1rho 成像，共进行 3 次扫描。扫描 1 和 2 之间的时间间隔为 30 分钟（组内），扫描 3 于 14 天后进行（组间）。在每次扫描中都获得正常组织（腮腺、腭扁桃体、翼内肌和舌）的 T1rho 值。计算正常组织的组内扫描（扫描 1 与 2）和组间扫描（扫描 1 与 3）的内类系数（ICC）、个体内变异系数（wCoV）和重复性系数（RC）。
正常组织 T1rho 值的 ICC 在组内扫描中为极好（0.83-0.97），在组间扫描中为高（0.71-0.80）。wCoV 显示组内扫描的范围较小（2.46%-3.30%），组间扫描的范围稍大（3.27%-6.51%）。T1rho 的最大和最小 wCoV 分别见于腮腺和肌肉。T1rho 的 RC 在组内和组间之间因组织而异，在组间扫描时腮腺的最大 RC 为 10.07msec。
T1rho 成像是一种头部和颈部的重复性定量 MRI 序列，但在分析时应考虑组织间 T1rho 值的差异。
