Zhonghua Nei Ke Za Zhi. 2021 Jan 1;60(1):13-21. doi: 10.3760/cma.j.cn112138-20201102-00914.
Glucocorticoid induced osteoporosis (GIOP) is the most common secondary osteoporosis. The prevention and treatment of the disease need urgent attention. In 2013, the Chinese Rheumatology Association of Chinese Medical Association proposed the Chinese consensus on the diagnosis and treatment of GIOP. Recently, great progress was harvested in epidemiology, fracture risk assessment and pharmaceutical therapy of GIOP. Because of the wide usage of glucocorticoids, a multidisciplinary team has updated the consensus of GIOP under the leadership of several scientific and academic committees. Applying the grading of recommendations assessment, development and evaluation (GRADE) approach, this consensus provides detailed recommendations for several important issues such as stratified assessment of fractures, treatments under different stratification, conversion, maintenance and withdraw, and management of special patients. This consensus is intended to serve as a tool for Chinese clinicians to standardize prevention and treatment of the disease and to improve medical care for these patients.
糖皮质激素性骨质疏松症(GIOP)是最常见的继发性骨质疏松症。该病的预防和治疗亟待关注。2013年,中华医学会风湿病学分会提出了GIOP诊断和治疗的中国专家共识。近年来,GIOP在流行病学、骨折风险评估及药物治疗方面取得了很大进展。由于糖皮质激素的广泛应用,多学科团队在多个科学学术委员会的领导下更新了GIOP的共识。本共识采用推荐意见分级评估、制定与评价(GRADE)方法,针对骨折分层评估、不同分层下的治疗、转换、维持及撤药以及特殊患者管理等重要问题提供了详细建议。本共识旨在为中国临床医生规范该病的防治提供工具,提高对这些患者的医疗照护水平。