School of Medicine, Tehran University of Medical Sciences, Tehran,Iran.
Experimental Medicine Research Center, Tehran University of Medical Center, Tehran,Iran.
Infect Disord Drug Targets. 2021;21(8):e160921189885. doi: 10.2174/1871526520666210104151849.
The novel coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), was announced as a pandemic in March 2020. Different diagnostic laboratory tests have been used to detect the infection. Each diagnostic tool, such as Chest Computed tomography (CT) imaging, genome sequencing, nucleic acid amplification methods, whole genome sequencing, microarray, and serology testing have several advantages and disadvantages. Nucleic acid amplification methods are better diagnostic tools for the detection of SARS-CoV-2 in early stages of the infection, while serological tests are more appropriate for the recognition of previously infected patients. In this review, we will briefly consider each diagnostic method, and discuss its pros and cons.
新型冠状病毒病 2019（COVID-19），由严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2）引起，于 2020 年 3 月宣布为大流行。不同的诊断实验室检测方法被用于检测感染。每种诊断工具，如胸部计算机断层扫描（CT）成像、基因组测序、核酸扩增方法、全基因组测序、微阵列和血清学检测都有其优缺点。核酸扩增方法是在感染早期检测 SARS-CoV-2 的更好的诊断工具，而血清学检测更适合识别以前感染过的患者。在这篇综述中，我们将简要考虑每种诊断方法，并讨论其优缺点。
