通过流式细胞术分析检测膀胱切除术后尿道残余组织中的癌

Detection of carcinoma in the post-cystectomy urethral remnant by flow cytometric analysis.

作者信息

Hermansen D K, Badalament R A, Whitmore W F, Fair W R, Melamed M R

机构信息

Department of Surgery (Urologic Service), Memorial Sloan-Kettering Cancer Center, New York, New York 10021.

出版信息

J Urol. 1988 Feb;139(2):304-7. doi: 10.1016/s0022-5347(17)42393-7.

DOI:10.1016/s0022-5347(17)42393-7

PMID:3339729

Abstract

Following radical cystoprostatectomy for bladder cancer patients must be monitored for carcinoma of the urethral remnant. Cytological examination of urethral washings has proved to be a useful alternative to urethroscopy and urethrography. Urethral irrigation specimens also can be evaluated objectively by flow cytometry. In each of 4 patients in whom carcinoma developed in the urethral remnant analysis of urethral irrigation by flow cytometry was positive and comparable to results of urethral irrigation cytology. Flow cytometry is an objective and apparently reliable diagnostic test for malignancy in the urethral remnant.

摘要

对于膀胱癌患者，在根治性膀胱前列腺切除术后，必须对尿道残端癌进行监测。尿道冲洗液的细胞学检查已被证明是尿道镜检查和尿道造影的一种有用替代方法。尿道冲洗标本也可通过流式细胞术进行客观评估。在4例尿道残端发生癌的患者中，通过流式细胞术对尿道冲洗液进行分析均呈阳性，且与尿道冲洗液细胞学检查结果相当。流式细胞术是一种客观且显然可靠的尿道残端恶性肿瘤诊断方法。