Liu Hongling, Yang Yang
Obstetrics Ward 3, Cangzhou Central Hospital, Xinhua West Road, Cangzhou, 061000, Hebei, China.
Ann Gen Psychiatry. 2021 Jan 4;20(1):2. doi: 10.1186/s12991-020-00320-4.
Anxiety and postpartum depression are the most common psychological problems in women after delivery. Cognitive behavior intervention has been reported to have an effect in the therapy of postpartum depression. This research aimed to investigate whether cognitive behavior intervention could prevent the pathogenesis of postpartum depression in primiparous women.
In this randomized controlled trial, primiparous women who were prone to postpartum depression were recruited. Participates in the control group received routine postpartum care and those in the intervention group received both routine postpartum care and cognitive behavior intervention. Hamilton Depression Scale (HAMD), Hamilton Anxiety Scale (HAMA), Edinburgh Postpartum Depression Scale (EPDS) and Pittsburgh Sleep Quality Index (PSQI) were evaluated before and after the intervention.
In the intervention group, the post-intervention scores of HAMA, HAMD, EPDS and PSQI were all significantly lower than the baseline scores (p = 0.034, p = 0.038, p = 0.004, p = 0.014, respectively). The proportion of participants with postpartum depression in the intervention group (11.5%) was significantly lower than the control group (24.3%) after the 6-week intervention. Participants in the intervention group were significantly more satisfied with the care than those in the control group (p = 0.032).
This research provided evidence that cognitive behavioral intervention in postpartum period could alleviate anxiety and depression in primiparous women, and inhibit the pathogenesis of postpartum depression. Trial registry This clinical trial was registered in the Chinese Clinical Trial Registry (ChiCTR2000040076).
焦虑和产后抑郁是女性产后最常见的心理问题。据报道,认知行为干预对产后抑郁的治疗有效果。本研究旨在调查认知行为干预是否能预防初产妇产后抑郁的发病机制。
在这项随机对照试验中,招募了易患产后抑郁的初产妇。对照组参与者接受常规产后护理,干预组参与者接受常规产后护理和认知行为干预。在干预前后评估汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)、爱丁堡产后抑郁量表(EPDS)和匹兹堡睡眠质量指数(PSQI)。
在干预组中,干预后HAMA、HAMD、EPDS和PSQI的得分均显著低于基线得分(分别为p = 0.034、p = 0.038、p = 0.004、p = 0.014)。经过6周的干预后,干预组产后抑郁参与者的比例(11.5%)显著低于对照组(24.3%)。干预组参与者对护理的满意度显著高于对照组(p = 0.032)。
本研究提供了证据,表明产后认知行为干预可以减轻初产妇的焦虑和抑郁,并抑制产后抑郁的发病机制。试验注册 本临床试验已在中国临床试验注册中心注册(ChiCTR2000040076)。