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以黑人为主的青少年 1 型糖尿病患者糖化血红蛋白轨迹的预测因素。

Predictors of HbA1c Trajectories in Predominantly Black Adolescents With Type 1 Diabetes.

机构信息

Department of Psychology, The University of Memphis.

Division of Pediatric Endocrinology & Diabetes, University of Tennessee Health Science Center.

出版信息

J Pediatr Psychol. 2021 Mar 18;46(3):241-250. doi: 10.1093/jpepsy/jsaa124.

DOI:10.1093/jpepsy/jsaa124
PMID:33398334
Abstract

OBJECTIVE

Following the Journal of Pediatric Psychology's special edition on health disparities, calling for Phase 2 research exploring mechanisms of racial groups in health disparities, this study aims to explore social information processing predictors of longitudinal hemoglobin A1c (HbA1c) trajectories in a racially diverse group of adolescents. The social information processing model of glycemic control in type 1 diabetes (T1D) posits that adolescents who make negative attributions about reactions of friends are likely to find adherence difficult in social situations, have increased stress, and have suboptimal glycemic control.

METHODS

One hundred eighty-four youth with T1D completed self-report measures and HbA1c at three time points within 1 year was extracted from medical records. Growth mixture modeling empirically derived classes of HbA1c trajectories and explored predictive relationships of social information processing variables, demographics, and diabetes characteristics.

RESULTS

Three classes emerged: High Decelerating, Mid-High Accelerating, and Near-Optimal Accelerating. Black/African American participants were highly likely to be in the High and Mid-High groups. Higher anticipated adherence difficulties in social situations predicted increased odds of being in the Mid-High versus Near-Optimal HbA1c group. Increased diabetes stress predicted increased odds of being in the High versus Near-Optimal and Mid-High groups.

CONCLUSIONS

Continuing research on mechanisms behind this health disparity is necessary with more representation from varied racial and ethnic groups. Equal access to diabetes technology and psychosocial treatments are recommended and implications for clinical intervention development are discussed.

摘要

目的

继《儿科心理学杂志》关于健康差异的特刊之后,呼吁开展第二阶段研究,探索健康差异中不同种族群体的机制,本研究旨在探索社会信息处理对不同种族青少年血红蛋白 A1c(HbA1c)纵向轨迹的预测因素。1 型糖尿病(T1D)血糖控制的社会信息处理模型假设,对朋友反应做出负面归因的青少年在社交情境中可能难以坚持治疗,压力增加,血糖控制不佳。

方法

184 名青少年 T1D 患者在 1 年内完成了 3 次自我报告测量和 HbA1c,从病历中提取。增长混合建模实证衍生出 HbA1c 轨迹的类别,并探讨了社会信息处理变量、人口统计学和糖尿病特征的预测关系。

结果

出现了 3 个类别:高减速、中高加速和接近最佳加速。黑人和/或非裔美国参与者极有可能处于高和中高组。在社交情境中预计坚持治疗的困难增加,预示着中高组与接近最佳 HbA1c 组相比,可能性更高。糖尿病应激增加预示着在高组与接近最佳和中高组相比,可能性更高。

结论

需要对这种健康差异背后的机制进行更多的研究,包括来自不同种族和族裔群体的更多代表性。建议平等获得糖尿病技术和心理社会治疗,并讨论了临床干预措施的发展。

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