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[微生物组测序与分析专家共识]

[Expert consensus on microbiome sequencing and analysis].

作者信息

Duan Yunfeng, Wang Shengyue, Chen Yubao, Yang Ruifu, Li Houkai, Zhu Huaiqiu, Tong Yigang, Wu Wenbin, Fu Yu, Hu Songnian, Wang Jun, Xin Yuhua, Zhao Fangqing, Bao Yiming, Zhang Wen, Li Juan, Zeng Ming, Niu Haitao, Zhou Xin, Li Yan, Cui Shenghui, Yuan Jing, Li Junhua, Wang Jiayi, Liu Donglai, Ni Ming, Sun Qing, Deng Ye, Zhu Baoli

机构信息

Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

出版信息

Sheng Wu Gong Cheng Xue Bao. 2020 Dec 25;36(12):2516-2524. doi: 10.13345/j.cjb.200386.

Abstract

In the past ten years, the research and application of microbiome has continued to increase. The microbiome has gradually become the research focus in the fields of life science, environmental science, and medicine. Meanwhile, many countries and organizations around the world are launching their own microbiome projects and conducting a multi-faceted layout, striving to gain a strategic position in this promising field. In addition, whether it is scientific research or industrial applications, there has been a climax of research and a wave of investment and financing, accordingly, products and services related to the microbiome are constantly emerging. However, due to the rapid development of microbiome sequencing and analysis related technologies and methods, the research and application from various countries have not yet unified on the standards of technology, programs, and data. Domestic industry participants also have insufficient understanding of the microbiome. New methods, technologies, and theories have not yet been fully accepted and used. In addition, some of the existing standards and guidelines are too general with poor practicality. This not only causes obstacles in the integration of scientific research data and waste of resources, but also gives related companies unfair competition opportunity. More importantly, China still lacks national standards related to the microbiome, and the national microbiome project is still in the process of preparation. In this context, the experts and practitioners of the microbiome worked together and developed the consensus of experts. It can not only guide domestic scientific research and industrial institutions to regulate the production, learning and research of the microbiome, the application can also provide reference technical basis for the relevant national functional departments, protect the scale and standardized corporate company's interests, strengthen industry self-discipline, avoid unregulated enterprises from disrupting the market, and ultimately promote the benign development of microbiome-related industries.

摘要

在过去十年中,微生物组的研究与应用持续增加。微生物组已逐渐成为生命科学、环境科学和医学领域的研究重点。与此同时,世界上许多国家和组织都在启动各自的微生物组项目并进行多方面布局,力争在这个前景广阔的领域占据战略地位。此外,无论是科研还是工业应用,都出现了研究高潮以及投资和融资热潮,相应地,与微生物组相关的产品和服务不断涌现。然而,由于微生物组测序及分析相关技术和方法发展迅速,各国的研究与应用在技术标准、方案和数据方面尚未统一。国内行业参与者对微生物组的了解也不足。新的方法、技术和理论尚未得到充分接受和应用。此外,一些现有标准和指南过于笼统,实用性差。这不仅在科研数据整合方面造成障碍、浪费资源,还给予相关企业不公平竞争机会。更重要的是,中国仍缺乏与微生物组相关的国家标准,国家微生物组项目仍在筹备过程中。在此背景下,微生物组领域的专家和从业者共同努力,制定了专家共识。它不仅能指导国内科研和产业机构规范微生物组的生产、学习和研究,还可为国家相关职能部门提供参考技术依据,保护规模化、规范化企业公司的利益,加强行业自律,避免无规范企业扰乱市场,最终促进微生物组相关产业的良性发展。

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