临床药师利用计算机化胰岛素剂量调整算法对连续血糖监测结果进行有效应用——概念验证。
Effective use of computerized insulin dose adjustment algorithms on continuous glucose monitoring results by a clinical pharmacist - Proof-of-concept.
作者信息
Davidson Mayer B, Davidson Seth Joshua
机构信息
Charles R. Drew University, Los Angeles, California, USA.
Mellitus Health, Inc, Los Angeles, California, USA.
出版信息
J Diabetes. 2021 Jan 5. doi: 10.1111/1753-0407.13154.
Highlights A clinical pharmacist using recommendations of Food and Drug Administration-cleared computerized insulin dose adjustment algorithms based on analyses of glucose readings from continuous glucose monitoring (Abbot Free Style Pro) in 13 poorly controlled insulin-requiring diabetic patients increased time in target range of 3.9 to 10.0 mmol/L from 29% to 51% and decreased time in range of >13.9 mmol/L from 43% to 23% (both P = 0.01) after 3 months. Glycated hemoglobin (HbA1c) levels (±SD) fell from 102 (±15) to 67 (±10) mmol/mol (P < 10 ).
要点
一名临床药剂师依据美国食品药品监督管理局批准的计算机化胰岛素剂量调整算法的建议，对13名胰岛素控制不佳的糖尿病患者进行了分析，这些分析基于连续血糖监测（雅培自由风格专业版）的血糖读数。3个月后，目标血糖范围在3.9至10.0毫摩尔/升的时间从29%增加到51%，血糖范围大于13.9毫摩尔/升的时间从43%降至23%（两者P = 0.01）。糖化血红蛋白（HbA1c）水平（±标准差）从102（±15）降至67（±10）毫摩尔/摩尔（P < 0.01）。
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