Saldías Peñafiel Fernando, Brockmann Veloso Pablo, Santín Martínez Julia, Fuentes-López Eduardo, Leiva Rodríguez Isabel, Valdivia Cabrera Gonzalo
Departamento de Enfermedades Respiratorias, División de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Departamento de Cardiología y Respiratorio Pediátrico, División de Pediatría, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Med Chil. 2020 Jul;148(7):895-905. doi: 10.4067/S0034-98872020000700895.
Obstructive sleep apnea syndrome (OSAS) affects approximately 10%-20% of adults and is associated with obesity, hypertension and metabolic syndrome.
To assess the prevalence and risk factors associated with OSAS in Chilean adults.
A standardized sleep questionnaire and respiratory polygraphy at home were conducted on adults aged 18 years or more, residing in the Metropolitan Region and enrolled in the 2016/17 National Health Survey.
Two-hundred and five people between 18 and 84 years old (46% men, mean age 50 years) underwent overnight respiratory polygraphy at home. The estimated obstructive sleep apnea prevalence was 49% (62% men, 31% women) considering an apnea-hypopnea index ≥ 5 respiratory events/hour, and 16% (21% men, 13% women) considering an apnea-hypopnea index ≥ 15 respiratory events/hour. The prevalence of obstructive sleep apnea continuously increased along with age for men and women, with a later onset for women. Age, gender, body mass index, cervical and waist circumference, snoring, reporting of apnea by proxies, self-reported cardiovascular and metabolic diseases such as hypertension, diabetes and dyslipidemia, were significantly associated with OSAS. No association was found with insomnia and daytime sleepiness.
The prevalence and risk factors associated to obstructive sleep apnea syndrome were high among these adults.
阻塞性睡眠呼吸暂停综合征(OSAS)影响约10%-20%的成年人,且与肥胖、高血压和代谢综合征相关。
评估智利成年人中OSAS的患病率及相关危险因素。
对居住在首都大区、年龄在18岁及以上且参加了2016/17年全国健康调查的成年人进行标准化睡眠问卷和家庭呼吸多导睡眠监测。
205名年龄在18至84岁之间的人(46%为男性,平均年龄50岁)在家中接受了夜间呼吸多导睡眠监测。考虑呼吸暂停低通气指数≥5次呼吸事件/小时,阻塞性睡眠呼吸暂停的估计患病率为49%(男性62%,女性31%);考虑呼吸暂停低通气指数≥15次呼吸事件/小时,患病率为16%(男性21%,女性13%)。男性和女性阻塞性睡眠呼吸暂停的患病率均随年龄持续增加,女性发病较晚。年龄、性别、体重指数、颈围和腰围、打鼾、他人报告的呼吸暂停、自我报告的心血管和代谢疾病如高血压、糖尿病和血脂异常与OSAS显著相关。未发现与失眠和日间嗜睡有关联。
在这些成年人中,阻塞性睡眠呼吸暂停综合征的患病率及相关危险因素较高。