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西澳大利亚儿童糖尿病:描述性流行病学

Diabetes in Western Australian children: descriptive epidemiology.

作者信息

Glatthaar C, Whittall D E, Welborn T A, Gibson M J, Brooks B H, Ryan M M, Byrne G C

机构信息

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA.

出版信息

Med J Aust. 1988 Feb 1;148(3):117-23. doi: 10.5694/j.1326-5377.1988.tb112770.x.

Abstract

The prevalence and incidence of diabetes mellitus in the age group zero to 14 years in Western Australia were determined from a survey by means of Schools Health Services. Additional information from the State's computer-linked hospital records system, the State's only children's hospital, diabetic clinics and physicians enabled virtually complete ascertainment of cases of childhood diabetes. Only 60% of school-age diabetic children were known to school nurses before the survey, but the nurses were able to identify two-thirds of the remainder during the survey. Among non-Aboriginal children, the prevalence of diabetes in the age group zero to 14 years was 0.59 per 1000 children and the incidence was 12.3 per 100,000 children per year. These rates are somewhat lower than those that have been reported from the United Kingdom and North America, and substantially lower than the rates that were reported from Scandinavia. All but one of the diabetic children who were identified required insulin and were assumed to be insulin-dependent. An excess of boys was found. None of 8715 Aboriginal or part-Aboriginal children had insulin-dependent diabetes mellitus, which indicates that this racial group has a low prevalence of this condition. In case--control studies, which used questionnaires for parents, no significant trends were found in relation to the history of immunizations or of specific viral illnesses except for a past history of varicella which was less frequent in diabetic children. A past history of established breast-feeding (of more than one week) was less frequent in diabetic children, as was the ingestion of vitamin C supplements before the onset of diabetes. Some evidence for a seasonality of onset was obtained. The diabetic children were absent from school for more days and had more admissions to hospital than did non-diabetic children. The majority of diabetic children were prescribed insulin twice a day or more often (84%); performed home blood-glucose monitoring (74%); and attended hospital diabetic clinics (91%).

摘要

通过学校健康服务调查确定了西澳大利亚州0至14岁年龄组糖尿病的患病率和发病率。来自该州计算机联网的医院记录系统、该州唯一的儿童医院、糖尿病诊所和医生的额外信息,使得几乎能够完全查明儿童糖尿病病例。在调查之前,只有60%的学龄糖尿病儿童为学校护士所知,但护士们在调查期间能够识别其余三分之二的儿童。在非原住民儿童中,0至14岁年龄组糖尿病的患病率为每1000名儿童中有0.59例,发病率为每年每10万名儿童中有12.3例。这些比率略低于英国和北美的报告比率,且大大低于斯堪的纳维亚半岛报告的比率。所查明的糖尿病儿童中,除一名外均需胰岛素治疗,且被认为是胰岛素依赖型。发现男孩数量过多。8715名原住民或部分原住民儿童中无一例患有胰岛素依赖型糖尿病,这表明该种族群体中这种疾病的患病率较低。在针对家长的问卷调查的病例对照研究中,除水痘既往史在糖尿病儿童中较少见外,未发现与免疫接种史或特定病毒疾病史有关的显著趋势。糖尿病儿童中既往有确定的母乳喂养史(超过一周)的情况较少,糖尿病发病前摄入维生素C补充剂的情况也较少。获得了一些发病季节性的证据。糖尿病儿童缺课天数比非糖尿病儿童多,住院次数也更多。大多数糖尿病儿童每天注射胰岛素两次或更频繁(84%);进行家庭血糖监测(74%);并前往医院糖尿病诊所就诊(91%)。

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