坏死梭杆菌白细胞毒素对牛肝细胞的细胞毒性作用。
Cytotoxic effects of a leukocidin from Fusobacterium necrophorum on bovine hepatic cells.
作者信息
Ishii T, Kanoe M, Inoue T, Kai K, Blobel H
机构信息
Department of Veterinary Microbiology and Hygiene, Faculty of Agriculture, Yamaguchi University, Japan.
出版信息
Med Microbiol Immunol. 1988;177(1):27-32. doi: 10.1007/BF00190308.
PMID:3340060
Abstract
Cytotoxic effects of a leukocidin from Fusobacterium necrophorum were demonstrated on bovine hepatic cells. The cytotoxic response was dose-dependent and could be inhibited by homologous antiserum. Scanning electron microscopy revealed damaged hepatic cell surface. These findings indicated a pathogenic role of the leukocidin in F. necrophorum infections.
摘要
坏死梭杆菌白细胞毒素对牛肝细胞的细胞毒性作用得到证实。细胞毒性反应呈剂量依赖性，且可被同源抗血清抑制。扫描电子显微镜显示肝细胞表面受损。这些发现表明白细胞毒素在坏死梭杆菌感染中起致病作用。
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